Sökning: "lipid rafts"

Visar resultat 11 - 15 av 33 avhandlingar innehållade orden lipid rafts.

  1. 11. Involvement of lipid rafts in G protein-coupled monoamine receptor trafficking and signaling : a pharmacological approach

    Författare :Benita Sjögren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The present work focused on lipid raft-mediated modulation of signaling and trafficking of serotonin (5-HT) and dopamine receptors. The 5-HT system is one of the most complex neurotransmitter systems, with a wide distribution both in the CNS and in the periphery. LÄS MER

  3. 12. Prion-infection and Cellular Signaling : Influence of scrapie-infection on lipid raft-associated proteins

    Författare :Hanna Gyllberg; Katarina Bedecs; Albert Taraboulos; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; biokemi; Biochemistry;

    Sammanfattning : Prion diseases are a group of fatal neurodegenerative diseases affecting almost all mammals including humans. The diseases are caused by formation of the misfolded isoform of the cellular prion protein (PrPC) to the disease causing PrPSc. LÄS MER

  4. 13. Vpu-mediated intracellular targeting of HIV-1 core protein precursor Pr55[gag] and association of Pr55[gag] with lipid microdomains

    Författare :Kirsi Harila; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : HIV-1 has been suggested to use lipid rafts for assembly and budding. Lipid rafts can be separated from the bulk membranes by extraction with non-ionic detergents, such as Triton X-100 at cold, followed by a density gradient centrifugation. LÄS MER

  5. 14. Regulation of non-responsiveness and death in cytotoxic T cells by the agonistic potency of MHC : peptide ligands

    Författare :Michael Uhlin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CD8 T cells; APL; CTLs; non-responsiveness; AICD; lck; lipid rafts; partial agonism; TCR activation.;

    Sammanfattning : CD8+ T lymphocytes are important for immunological control of infections and tumors. The key interaction required to initiate the process of T cell activation is the engagement of the T cell receptor (TCR) with a major histocompatibility complex (MHC) class I/peptide complex on an antigen presenting cell (APC). LÄS MER

  7. 15. Leishmania donovani lipophosphoglycan : effects on actin and phagosomal maturation

    Författare :Åsa Holm; Maria Fällman; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Leishmania donovani promastigotes survive intracellularly in macrophages by inhibiting phagosomal maturation. This ability is conferred by surface lipophosphoglycan (LPG), which is transferred to the host-cell plasma and phagosomal membranes during phagocytosis. LÄS MER