Sökning: "lipid liquid crystals"

Visar resultat 1 - 5 av 17 avhandlingar innehållade orden lipid liquid crystals.

1. 1. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

   Författare :Lukas Boge; Martin Andersson; Lovisa Ringstad; RISE; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid crystals; liquid crystalline nanoparticles; cubosome; hexosome; phase behavior; antimicrobial peptide; AMP; glycerol monooleate; proteolysis; antimicrobial effect; antimicrobial resistance; bacterial membrane; membrane interaction; infection; topical delivery; pulmonary delivery;

   Sammanfattning : The development of antimicrobial resistance is a great challenge within health sectors worldwide. Thus, demand for new, efficient treatments is urgent in order to treat various bacterial infections. Antimicrobial peptides (AMPs) are a group of antibiotics that have gained more and more attraction in the past decade. LÄS MER

3. 2. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

   Författare :Lukas Boge; Chalmers tekniska högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; hexosome; antimicrobial peptide; cubosome; proteolysis; AMP; liquid crystalline nanoparticles; glycerol monooleate; Liquid crystals;

   Sammanfattning : The development of antimicrobial resistance is a great challenge within the health sector around the world. The demand for new efficient treatments is alarming in order to treat various bacterial infections in the near future. Antimicrobial peptides (AMPs) are a group of novel antibiotics that have gain more and more attraction the past decade. LÄS MER

4. 3. Small-Scale Sample Handling for Studies of Liquid Crystals and Lipid-Based Soft Matter

   Författare :Gabriel Ohlsson; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; fluorescence microscopy; nanocell; Microfluidics; aquaporins; liquid crystals; membrane transport; phase transitions; QCM-D; soft matter; lipid bilayer;

   Sammanfattning : In the field of sensing in general and biosensing in particular, there is a growing need for integratingminiaturised senor elements in microfluidic systems. The advantages are several, some of which being that the consumption of, often very expensive, sample material can be reduced; sampleexchange can be optimized; sensor performance in terms of detection limits can be improved and phenomena occurring on a very small, and even single-molecule, scale can be studied. LÄS MER

5. 4. Molecular Structure in Liquid Crystals Studied by NMR

   Författare :Johan Thaning; Arnold Maliniak; Claudio Zannoni; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NMR; Maximum Entropy; APME; Dipolar couplings; Liquid Crystals; Physical chemistry; Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

   Sammanfattning : This thesis is focused on structure determinations of molecules in liquid crystals using NMR. The systems described here exhibit orders ranging from nearly isotropic to essentially solid. LÄS MER

7. 5. Lipid sponge phase nanostructures as carriers for enzymes

   Författare :Maria Valldeperas Badell; NanoLund: Centre for Nanoscience; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sponge phase; lipid liquid crystals; DGMO; GMO-50; polysorbate 80; encapsulation of proteins; Aspartic protease; β-galactosidase; X-ray and neutron scattering; Raman spectroscopy; adsorption; cryo-TEM;

   Sammanfattning : Nonlamellar lipid liquid crystalline phases have many potential applications, such as for drug delivery, protein encapsulation or crystallization. Lipid liquid crystalline sponge phase (L3) has so far not been very much considered in these applications, in spite of apparent advantages in terms of its flexibility and capacity of forming large aqueous pores able to encapsulate large bioactive molecules. LÄS MER