Sökning: "lipase ca"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden lipase ca.

  1. 1. Monoglyceride Lipase and Hormone-Sensitive Lipase - Molecular and structural aspects

    Författare :Marie Karlsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genomic organisation; baculovirus-insect cells; catalytic triad; alfa beta hydrolase fold; tissue distribution; cDNA sequence; lipolysis; adipocyte; monoglyceride lipase; hormone-sensitive lipase; chromosomal localisation; Clinical biology; Klinisk biologi;

    Sammanfattning : Triglycerides in the adipocyte are hydrolysed by means of three consecutive reactions through the combined action of two lipases: hormone-sensitive lipase (HSL) and monoglyceride lipase (MGL). HSL catalyses the first and rate-limiting step, i.e. LÄS MER

  3. 2. Structure-function relationships of hormone-sensitive lipase

    Författare :Torben Österlund; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteins; mutagenesis; domain; fold; catalytic triad; lipase; structure; enzymology; Proteiner; enzymologi;

    Sammanfattning : The primary role of hormone-sensitive lipase (HSL), an 84 kDa enzyme of 768 amino acids (in the rat protein), is to hydrolyse stored triacylglycerols in adipocytes of white adipose tissue. Catecholamines and insulin regulate lipolysis through cellular signalling. LÄS MER

  4. 3. Aliphatic Polyesters for Soft Tissue Engineering : Development from Conventional Organometallic to Novel Enzymatic Catalysis

    Författare :Rajiv Kumar Srivastava; Ann-Christine Albertsson; Stanishaw Penzzek; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aliphatic polyester; 1; 5-dioxepan-2-one; ε-caprolactone; L-lactide; D-lactide; D; L-lactide; enzyme; lipase CA; lipase PS; Polymer chemistry; Polymerkemi;

    Sammanfattning : The development of macromolecules with defined structure and properties, aimed specifically for biomedical applications, has resulted in diverse biodegradable polymers with advanced architectures. Among them, aliphatic polyesters synthesized by ring-opening polymerization (ROP) of lactones and lactides have a leading position due to their good mechanical properties, hydrolyzability and biocompatibility. LÄS MER

  5. 4. Novel methods to synthesize aliphatic polyesters of vivid architectures

    Författare :Rajiv Srivastava; Ann-Christine Albertsson; Ronnie Palmgren; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Polyesters; 1; 5-dioxepan-2-one; Caprolactone; Sn Oct 2; Enzyme; Lipase-CA; Ring-Opening Polymerization; Architecture; Tissue Engineering; Polymer chemistry; Polymerkemi;

    Sammanfattning : Cross-linked films of ε-caprolactone (CL) and 1,5-dioxepan-2-one (DXO) having various mole fractions of monomers and different cross-link densities were prepared using 2,2’-bis-(-caprolactone-4-yl) propane (BCP) as cross-linking agent and Sn(Oct)2 as catalyst. Reaction parameters were examined to optimize the film-forming conditions. LÄS MER

  7. 5. Determination of Fat-Soluble Vitamins in Foods Based on Supercritical Fluid Extraction

    Författare :Charlotta Turner; Kemiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Supercritical fluid extraction; Solvent collection; Solid phase trapping; SFE; Selectivity; Retinol; Milk powder; Lipase; Food; Enzymatic hydrolysis; Alcoholysis; Candida antarctica; Tocopherol; Vitamins; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Sample clean-up methodologies based on supercritical fluid extraction (SFE) have been developed for determination of fat-soluble vitamins in foods. This thesis focuses on method development, stressing important issues concerning sample pre-treatment, extraction conditions and collection parameters. LÄS MER