Sökning: "linoleic acid"

Visar resultat 11 - 15 av 55 avhandlingar innehållade orden linoleic acid.

  1. 11. Diet and inflammation : the role of nitrate and conjugated linoleic acid

    Författare :Cecilia Jädert; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A diet rich in vegetables and unsaturated fatty acids is associated with a lower risk of major diseases including cardiovascular disease, type 2 diabetes and chronic inflammation. Yet, despite extensive research, the active component(s) responsible for these effects has not been pinpointed and studies with single nutrients have been largely unsuccessful. LÄS MER

  2. 12. Discovery of Novel Fatty Acid Dioxygenases and Cytochromes P450 : Mechanisms of Oxylipin Biosynthesis in Pathogenic Fungi

    Författare :Inga Hoffmann; Ernst H Oliw; Alan R Brash; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Fusion protein; Linoleate diol synthase; Allene oxide synthase; Cyclooxygenase; Oxygenase; HPLC; Mass spectrometry; Hydroperoxide isomerase; Aspergillus; Fusarium oxysporum; Pharmaceutical Biochemistry; Farmaceutisk biokemi; Farmaceutisk farmakologi; Pharmaceutical Pharmacology; Farmaceutisk vetenskap; Pharmaceutical Science;

    Sammanfattning : Dioxygenase-cytochrome P450 (DOX-CYP) fusion enzymes are present in diverse human and plant pathogenic fungi. They oxygenate fatty acids to lipid mediators which have regula­tory functions in fungal development and toxin production. LÄS MER

  3. 13. Catalytic and Structural Properties of Heme-containing Fatty Acid Dioxygenases : Similarities of Fungal Dioxygenases and Cyclooxygenases

    Författare :Ulrike Garscha; Ernst Oliw; Per-Johan Jakobsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dioxygenase; prostaglandin H synthase; Gaeumannomyces graminis; Aspergilli; hydroperoxide isomerase; linoleate diol synthase; cytochrome P450; oxylipin; Pharmaceutical pharmacology; Farmaceutisk farmakologi; Farmaceutisk farmakologi; Pharmaceutical Pharmacology;

    Sammanfattning : 7,8-Linoleate diol synthase (7,8-LDS) of the take-all pathogen of wheat, Gaeumannomyces graminis, converts linoleic acid to 8R-hydroperoxyoctadecadienoic acid (8-HPODE) by 8-dioxygenase activity (8-DOX), and further isomerizes the hydroperoxide to 7S,8S-dihydroxyoctadecadienoic acid (7,8-DiHODE) by hydroperoxide isomerase activity. Sequence alignment showed homology to prostaglandin H synthase (PGHS), and both enzymes share structural and catalytic properties. LÄS MER

  4. 14. Fatty Acid Desaturase Activities in Metabolic Syndrome and Cardiovascular Disease : Special Reference to Stearoyl-CoA-Desaturase and Biomarkers of Dietary Fat

    Författare :Eva Warensjö; Ulf Risérus; Bengt Vessby; Tommy Cederholm; David Laaksonen; Uppsala universitet; []
    Nyckelord :Nutrition; Fatty acids; Dietary fat; Biomarker; Metabolic Syndrome; Mortality; Obesity; Insulin Sensitivity; Epidemiology; Estimated desaturase activities; Stearoyl-CoA-desaturase; delta-6-desaturase; delta-5-desaturase; Single Nucleotide Polymorphism; Dietary Intervention; Rapeseed oil; Saturated fat; SCD1; Näringslära;

    Sammanfattning : The development of the metabolic syndrome (MetS) and cardiovascular diseases have been suggested to be influenced more by the quality than the amount of dietary fat. The FA composition of serum lipids may be used as biomarkers of dietary fat quality. LÄS MER

  5. 15. Movement patterns and displacement of a soil insect

    Författare :Elna Nilsson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; attraction; repellence; fatty acid; Ecology; Ekologi; alarm; autoregressive model; autocorrelation; random walk; Protaphorura armata; Collembola; migration; dispersal; movement; displacement;

    Sammanfattning : Movement and dispersal are important determinants of the spatial distribution and persistence of animal populations in a heterogeneous environment. I studied the small-scale movement pattern of a soil-living insect, Protaphorura armata (Collembola) by using a video-equipment. LÄS MER