Sökning: "linear transduction"

Visar resultat 1 - 5 av 7 avhandlingar innehållade orden linear transduction.

1. 1. Translation as Linear Transduction : Models and Algorithms for Efficient Learning in Statistical Machine Translation

   Författare :Markus Saers; Joakim Nivre; Anna Sågvall Hein; Dekai Wu; Kevin Knight; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; linear transduction; linear transduction grammar; inversion transduction; zipper finite-state automaton; zipper finite-state transducer; formal language theory; formal transduction theory; translation; automatic translation; machine translation; statistical machine translation; Computational linguistics; Datorlingvistik; Language technology; Språkteknologi; Computational Linguistics; Datorlingvistik;

   Sammanfattning : Automatic translation has seen tremendous progress in recent years, mainly thanks to statistical methods applied to large parallel corpora. Transductions represent a principled approach to modeling translation, but existing transduction classes are either not expressive enough to capture structural regularities between natural languages or too complex to support efficient statistical induction on a large scale. LÄS MER

3. 2. Exploring conditional motif-based protein interactions in health and disease

   Författare :Johanna Kliche; Ylva Ivarsson; Ulrich Stelzl; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ProP-PD; protein-protein interaction; short linear motif; phosphorylation; disease mutation; Biokemi; Biochemistry;

   Sammanfattning : Protein-protein interactions (PPIs) orchestrate a variety of cellular events, ranging from signal transduction, scaffolding to subcellular localisation. A subclass of PPIs is mediated by short linear motifs, which are short amino acid stretches found in the intrinsically disordered regions of the proteome. LÄS MER

4. 3. Analysis of PDGF receptor internalization and signaling using proximity ligation assays

   Författare :Marie Rubin Sander; Ola Söderberg; Cristina Al-Khalili Szigyarto; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PDGFRβ; dynamin; proteolytic cleavage; signaling; internalization; protein-protein interaction; short linear motif; viral hijack; in situ PLA; Molboolean;

   Sammanfattning : Cell signaling is mediated by signaling proteins that relay the signal in an intricate network of interactions before the signal is translated into a biological response. Short linear motifs (SLiMs) in intrinsically disordered regions of proteins serve as docking sites for protein interaction in all aspects of cell regulation including signal transduction. LÄS MER

5. 4. Promiscuity and Selectivity in Phosphoryl Transferases

   Författare :Alexandre Barrozo; Shina Kamerlin; Qiang Cui; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; phosphate chemistry; linear free energy relationships; phosphatase; catalytic promiscuity; empirical valence bond approach; alkaline phosphatase;

   Sammanfattning : Phosphoryl transfers are essential chemical reactions in key life processes, including energy production, signal transduction and protein synthesis. They are known for having extremely low reaction rates in aqueous solution, reaching the scale of millions of years. LÄS MER

7. 5. Tailoring Conducting Polymer Interface for Sensing and Biosensing

   Författare :Lingyin Meng; Wing Cheung Mak; Anthony Turner; Daniel Filippini; Mikhail Vagin; Man Bock Gu; Linköpings universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Conducting polymer; Interface; Sensing; Biosensing; Bioelectronics;

   Sammanfattning : The routine measurement of significant physiological and biochemical parameters has become increasingly important for health monitoring especially in the cases of elderly people, infants, patients with chronic diseases, athletes and soldiers etc. Monitoring is used to assess both physical fitness level and for disease diagnosis and treatment. LÄS MER