Sökning: "linear epitopes"

Visar resultat 1 - 5 av 15 avhandlingar innehållade orden linear epitopes.

  1. 1. Seroepidemiology of vaccine-preventable and emerging RNA viruses in Rwanda

    Författare :Eric Seruyange; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Seroprevalence; measles virus; rubella virus; Zika virus; West Nile virus; chikungunya virus; tick-borne encephalitis virus; mosquitoes; linear epitopes; Rwanda; Sweden;

    Sammanfattning : Abstract Infectious diseases are a leading cause of death in sub-Saharan Africa, and in Rwanda diarrhea, lower respiratory and other common infections are linked to high mortality and morbidity. For children ... LÄS MER

  3. 2. Cyclic peptides as biological tools : Applications for diagnosis and therapeutics in rheumatoid arthritis and COVID-19

    Författare :Camilla Eriksson; Ulf Göransson; Sunithi Gunasekera; Christian Becker; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Scaffold peptides; peptide grafting; rheumatoid arthritis; SARS-CoV-2; autoantibodies; peptide synthesis; pharmacognosy;

    Sammanfattning : The overall aims of the projects included in this thesis were to design, synthesize and evaluate cyclic peptide scaffolds grafted with biological epitopes for their ability to bind antibodies in rheumatoid arthritis and COVID-19 sera. One of the main outcomes of this thesis was the observation that scaffold peptides grafted with target epitopes efficiently neutralized anti-citrullinated protein autoantibodies (ACPA) from rheumatoid arthritis patients. LÄS MER

  4. 3. Characterization of antibody specificity using peptide array technologies

    Författare :Björn Forsström; Mathias Uhlén; Markus Templin; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antibody; Epitope mapping; Peptide array; Suspension bead array; Antigen; Specificity; Cross-reactivity; Immunization; Immunogenicity; Bioteknologi; Biotechnology;

    Sammanfattning : Antibodies play an important role in the natural immune response to invading pathogens. The strong and specific binding to their antigens also make them indispensable tools for research, diagnostics and therapy. LÄS MER

  5. 4. Grid and High-Performance Computing for Applied Bioinformatics

    Författare :Jorge Andrade; Jacob Odeberg; Luciano Milanesi; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Grid computing; bioinformatics; genomics; proteomics; Bioinformatics; Bioinformatik;

    Sammanfattning : The beginning of the twenty-first century has been characterized by an explosion of biological information. The avalanche of data grows daily and arises as a consequence of advances in the fields of molecular biology and genomics and proteomics. LÄS MER

  7. 5. Glycoprotein G of Herpes simplex virus type 2. Antigenicity and genetic variability

    Författare :Jan-Åke Liljeqvist; Göteborgs universitet; []
    Nyckelord :Herpes simplex virus type 2; glycoprotein G; antigenic regions; sequence variability;

    Sammanfattning : Herpes simplex virus type 2 (HSV-2) causes genital lesions, meningitis and occasionally, severe neonatal infections. Globally HSV-2 infection is one of the most common sexually transmitted diseases. LÄS MER