Sökning: "ligands"

Visar resultat 1 - 5 av 934 avhandlingar innehållade ordet ligands.

  1. 1. Galanin receptor ligands

    Författare :Johan Runesson; Ülo Langel; Lena Mäler; Stockholms universitet; []
    Nyckelord :Galanin; GALP; GPCR; Agonist; GalR; Chimeric peptide; Inositol phosphate production; Receptor specificity; Neurochemistry and Molecular Neurobiology; neurokemi med molekylär neurobiologi;

    Sammanfattning : In the nervous system galanin primarily displays a modulatory role. The galaninergic system consists of a number of bioactive peptides with a highly plastic expression pattern and three different receptors. The lack of receptor subtype selective ligands and antibodies have severely hampered the charac-terization of this system. LÄS MER

  3. 2. Galanin receptor ligands : Design, synthesis, characterization and biological effects

    Författare :Kristin Webling; Ülo Langel; Tore Bengtsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

    Sammanfattning : Galanin is a 29/30 amino acid long bioactive peptide discovered over 30 years ago when C-terminally amidated peptides were isolated from porcine intestines. The name galanin originates from a combination of the first and last amino acids - G from glycine and the rest from alanine. LÄS MER

  4. 3. Galanin receptor ligands : agonists and the first antagonists

    Författare :Tiit Land; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 4. Oxaline-containing ligands : synthesis and applications

    Författare :Emmanuel Macedo; KTH; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  7. 5. Asymmetric Hydrogenations : Syntheses of Ligands and Expansion of Substrate Scope

    Författare :Pradeep Cheruku; Pher Andesson; Jay Siegel; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Catalysis; Asymmetric; Hydrogenations; Reductions; Olefins; Imines; Enol phosphinates; Transition metal; Complexes; Iridium; Enamines; Ruthenium; Ligands; Trifluoromethyl; Diphenylvinylphosphine oxides; Vinyl phosphonates; Chemistry; Kemi;

    Sammanfattning : Asymmetric hydrogenation has emerged as a versatile methodology to obtain a wide range of chiral precursors. This thesis focused on the synthesis of new chiral ligands and the expansion of the substrate scope of asymmetric hydrogenations. LÄS MER