Sökning: "ligand and solvent effects"

Visar resultat 1 - 5 av 19 avhandlingar innehållade orden ligand and solvent effects.

1. 1. On the Diluent and Solvent Effects in Liquid-Liquid Extraction Systems based on Bis-triazine-bipyridine (BTBP) ligands

   Författare :Elin Löfström Engdahl; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Solvent effects; Diluent effects; GANEX; Interfacial tension; Density;

   Sammanfattning : Used nuclear fuel is dangerous for mankind and her environment for a long time. If however, the minor actinides together with uranium and plutonium could be transmuted, i.e. transformed, into more shortlived or stable isotopes the volume of the waste could be significantly reduced together with a reduction in the radiotoxicity. LÄS MER

3. 2. Computational Analysis of Molecular Recognition Involving the Ribosome and a Voltage Gated K+ Channel

   Författare :Martin Andér; Johan Åqvist; Lennart Nilsson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; computer simulations; molecular dynamics; ligand binding; binding free energy; linear interaction energy; codon recognition; translation termination; release factor; voltage gated potassium ion channel; Kv1.5; Structural biology; Strukturbiologi; Biochemistry; Biokemi; Biokemi; Biochemistry;

   Sammanfattning : Over the last few decades, computer simulation techniques have been established as an essential tool for understanding biochemical processes. This thesis deals mainly with the application of free energy calculations to ribosomal complexes and a cardiac ion channel. LÄS MER

4. 3. Multiple Functions of Glutathione Transferases : A Study on Enzymatic Function, Regulatory Role and Distribution in Mouse and Man

   Författare :Maryam Edalat; Joseph De Pierre; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biokemi; Biochemistry; Biokemi; biokemi; Biochemistry;

   Sammanfattning : To cope with various endogenous toxin and xenobiotics nature has equipped the organisms with a proper protection system. Glutathione transferases (GSTs) are important components of the cellular defense against oxidative stress. These proteins appear to be suited for different tasks. LÄS MER

5. 4. Development and application of new chiral -amino alcohols in synthesis and catalysis : Use of 2-azanorboryl-3-methanols as common intermediates in synthesis and catalysis

   Författare :Pedro Pinho; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Asymmetric synthesis; hetero-Diels-Alder reactions; chiral cyclopentyl-amines; chiral ligands and catalysts; amino alcohols; asymmetric reductions; ruthenium transfer hydrogenation; oxazaborolidines; asymmetric additions; dialkylzinc reagents; Kemi; Chemistry; Kemi; organisk kemi; Organic Chemistry;

   Sammanfattning : The development and application of unnatural amino alcohols,prepared via hetero-Diels-Alder reactions,in synthesis and catalysis is described.The studies are concerned with the [i]scope of the hetero-Diels-Alder reaction and preparation of important intermediates in the synthesis of antiviral agents,[ii ]application of amino alcohols in the ruthenium transfer hydrogenation of ketones,[iii ]use of similar precursors in the in situ generation of oxazaborolidines for reduction of ketones,and [iv] development and application of new chiral auxiliaries for dialkylzinc additions to activated imines, respectively. LÄS MER

7. 5. Energy and Electron Transfer in Porphyrin-Based Donor--Bridge--Acceptor Systems

   Författare :Kristine Kilså; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; electron transfer; electronic coupling; donor--bridge--acceptor systems; quantum mechanical calculations; enhanced intersystem crossing; ligand and solvent effects; bridge mediation; energy transfer; porphyrin;

   Sammanfattning : The photophysical properties of supramolecular donor--bridge--acceptor systems have been investigated by spectroscopic and quantum mechanical methods. The systems consist of porphyrin donor and acceptor moieties linked by bridging chromophores of varying excitation energy, and are shown to be geometrically well-defined in terms of length and rotational conformation. LÄS MER