Sökning: "lifetime risk"

Visar resultat 21 - 25 av 186 avhandlingar innehållade orden lifetime risk.

  1. 21. Familial breast cancer : risk populations and their surveillance

    Författare :Anna von Wachenfeldt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Women carrying mutations in either BRCA 1 or BRCA2 have a lifetime risk of breast cancer of 80%. As little is known about the risk of other malignancies, apart from ovarian/tubal cancer in mutation carriers, the importance of other malignancies in a family with several cases of breast cancer is hard to evaluate. LÄS MER

  3. 22. Mortality Risk, Moral Hazard, and Mental Health: Essays in Applied Microeconomics

    Författare :Clara Fernström; Handelshögskolan i Stockholm; []
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

    Sammanfattning : This doctoral thesis consists of three self-contained chapters.“Dying and dissaving” analyses how individuals change saving behavior in response to new information about their expected lifetime. The author uses Swedish administrative data to link negative health shocks to subsequent saving behavior. LÄS MER

  4. 23. Tumors associated with Hereditary Nonpolyposis Colorectal Cancer: Defective Mismatch Repair and Familial Risk of Cancer

    Författare :Kajsa Ericson Lindquist; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; cancerology; Cytologi; onkologi; cancer; Multiple Tumors; Hereditary Nonpolyposis Colorectal Cancer; Cytology; Cohort study; Population based; Familial Risk of Cancer; Immunohistochemistry; MSH2; MSH6; MLH1; Microsatellite Instability; Soft Tissue Sarcomas; Cancer of the Upper Urinary Tract; Cancer of the Small Intestine; Colorectal Cancer;

    Sammanfattning : Inactivation of the DNA mismatch repair (MMR) system is a tumorigenic mechanism involved in 15-20% of tumor types such as colorectal and endometrial cancer and is specifically associated with the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) syndrome. These MMR defective tumors are characterized by microsatellite instability (MSI), a phenomenon that reflects alterations in length of repeated sequences, and 90% of MSI tumors show loss of immunohistochemical expression for the MMR protein affected. LÄS MER

  5. 24. Acetabular Revisions. Risk Factors and Prediction of Re-revision

    Författare :Maziar Mohaddes; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Osteoarthritis; Hip; Register studies; Radiostereometry; Acetabular revision; Trabecular metal;

    Sammanfattning : Hip replacement is a successful intervention when treating patients with hip osteoarthritis. Approximately 10% of all patients undergoing primary hip replacement surgery require further surgical interventions (revisions) during their lifetime. Acetabular component (cup) failure is the most common reason for a revision. LÄS MER

  7. 25. Out-of-field doses from proton therapy and doses from CBCT imaging : Risk of radiation-induced second cancer from modern radiotherapy

    Författare :Oscar Ardenfors; Irena Gudowska; Alexandru Dasu; Cathrine Jonsson; Pawel Olko; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Medical Radiation Physics; medicinsk strålningsfysik;

    Sammanfattning : The use of ionizing radiation for treatment of cancer diseases is continuously increasing as patient survival is improving and new treatment techniques are emerging. While this development is beneficial for curing primary tumors, concerns have been raised regarding the unwanted dose contribution to healthy tissues of patients and the associated risk of radiation-induced second cancer (RISC). LÄS MER