Sökning: "lidocaine"

Visar resultat 1 - 5 av 43 avhandlingar innehållade ordet lidocaine.

1. 1. Molecular Dynamics Investigations of Structure and Dynamics of Lipid Bilayers and Associated Anesthetics

   Författare :Carl-Johan Högberg; Alexander Lyubartsev; Lennart Nilsson; Stockholms universitet; []
   Nyckelord :DMPC; Molecular dynamics simulations; Anesthetics; Lidocaine; Physical Chemistry; fysikalisk kemi;

   Sammanfattning : Detailed understanding of lipid bilayers are of tremendous importance due to their role in many biological processes. This Thesis focuses on structural and dynamical properties of lipid bilayers and their interactions with locally acting anesthetics, studied by Molecular Dynamics simulations. LÄS MER

3. 2. Drug Transport and Metabolism in Rat and Human Intestine

   Författare :Sofia Berggren; Hans Lennernäs; Janet Hoogstraate; Patrick Augustijns; Uppsala universitet; []
   Nyckelord :Biopharmacy; Ussing chamber; microsome; single-pass perfusion; human; rat; intestine; permeability; efflux; P-glycoprotein; metabolism; cytochrome P450; ropivacaine; lidocaine; bupivacaine; Biofarmaci; PPX;

   Sammanfattning : One of the aims of this thesis was to investigate the involvement of efflux proteins, such as the P-glycoprotein (Pgp), in the drug transport in different regions of the rat and the human intestine. The intestinal extrusion of intracellularly formed CYP3A4 metabolites, including whether this extrusion might be mediated by Pgp, was also studied. LÄS MER

4. 3. Safety and efficacy of intracameral mydriatics in cataract surgery

   Författare :Björn Lundberg; Anders Behndig; Charlotta Zetterström; Umeå universitet; []
   Nyckelord :Ophtalmology; intracameral; mydriatics; pupil; cataract; phacoemulsification; lidocaine; phenylephrine; cyclopentolate; epinephrine; endothelial cell loss; Oftalmiatrik; oftalmiatrik; Ophtalmology;

   Sammanfattning : Background: In order to perform cataract surgery, adequate dilatation of the pupil is essential. This is traditionally achieved by preoperative topical mydriatic eye-drops, commonly cyclopentolate and phenylephrine. This routine has several disadvantages. First, the slow penetration through the cornea delays the onset of mydriasis. LÄS MER

5. 4. A new technique for postoperative pain management with local anesthetic after abdominal hysterectomy

   Författare :Andrea Perniola; Kjell Axelsson; Anil Gupta; Johan Lundberg; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; local anesthetics; postoperative pain; abdominal hysterectomy; intra-peritoneal; catheter; Lidocaine; Levobupivacaine; Medicin; Medicine;

   Sammanfattning : An abdominal hysterectomy (AH) is associated with moderate to severe postoperative pain. In this thesis, a new technique for postoperative pain managment has been studied in 200 patients: local anesthetic (LA) was administered intraperitoneally (IP) after elective AH. LÄS MER

7. 5. Studies on the overactive bladder with special reference to diagnosis, classification and surgical treatment

   Författare :Christer Edlund; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Unstable detrusor; overactive bladder; detrusor hyperreflexia; lidocaine; electric nerve stimulation; neuromodulation; sacral nerve stimulation; urodynamics.;

   Sammanfattning : The overactive bladder (OB) is a symptom of disturbed neuromuscular control of the lower urinary tract. The cause is sometimes obvious, but even a lesion that is minor and difficult to detect might be of significance. LÄS MER