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Visar resultat 1 - 5 av 9 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Aspects of chronic autoimmune thyroiditis in children and adolescents

   Författare :Johan Svensson; Pediatrisk endokrinologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescents; thyroid autoantibodies; enterovirus infection; thyroid ultrasonography; reference standard; goiter; chronic autoimmune thyroiditis; levothyroxine treatment; Medicin människa och djur ; Medicine human and vertebrates ; children;

   Sammanfattning : The aims of this thesis were to 1) compare different methods for detection of antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb), particulary in children with chronic autoimmune thyroditis (AIT), 2) investigate if maternal enterovirus infection is a risk factor for development of AIT in offspring, 3) ascertain the prevalence of thyroid autoantibodies in cord blood sera from children who later developed AIT, 4) develop a new reference standard for interpretation of normative thyroid volumes in Swedish children, and 5) evaluate the effect of Levothyroxine (L-thyroxine) treatment on thyroid size in children and adolescents with AIT. We found that 1) Methods based on radioimmunoassay (RIA) were more efficient in detecting both TgAb and TPOAb in children with AIT than methods based on agglutination. LÄS MER

3. 2. Recurrent unexplained first-trimester miscarriage. Effects of acetylcalicylic acid, platelet aggregation and thyroid disease

   Författare :Lennart Blomqvist; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Acetylsalicylic acid; recurrent miscarriage; platelet aggregation; pregnancy; early pregnancy; first-trimester; live birth; impedance aggregometry; thyroid stimulating hormone; levothyroxine; thyroid peroxidase antibody; arachidonic acid-induced platelet aggregation; platelet activators;

   Sammanfattning : Recurrent unexplained first-trimester miscarriage. Effects of acetylsalicylic acid, platelet aggregation and thyroid disease. Lennart Blomqvist, Department of Obstetrics and Gynecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sweden, 2019. LÄS MER

4. 3. Hyperthyroidism : a chronic disease?

   Författare :Gabriel Sjölin; Göran Wallin; Mikael Lantz; Laszlo Hegedus; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hyperthyroidism; Graves’ disease; toxic nodular goitre; longterm follow-up; Quality of Life; radioactivated iodine; antithyroid drugs; thyroidectomy; index patient;

   Sammanfattning : During 2003-2005, approximately 3,000 de novo hyperthyroid patients were collected in Sweden and became one of the world's largest hyperthyroidism studies. This dissertation shows that many people diagnosed with hyperthyroidism live with its impacts even after excess of thyroid hormone has ended. LÄS MER

5. 4. Endocrine and paracrine factors related to pregnancy and infertility

   Författare :Frida Hosseini Akram; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Unexplained infertility, one of the common gynecological disorders, affecting 10 to 15 % of women worldwide. Recurrent pregnancy loss affects approximately 1 to 3 % of pregnant women with an unknown etiology in 50 % of cases. Endocrine dysfunctions, including thyroid dysfunction, are one of the related factors to female reproductive disturbances. LÄS MER

7. 5. Hypothyroidism and Pregnancy

   Författare :Michaela Granfors; Anna-Karin Wikström; Inger Sundström-Poromaa; Helena Åkerud; Ulla Feldt-Rasmussen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phosphodiesterase 8B; recurrent miscarriage; single nucleotide polymorphism; thyroid; guidelines; hypothyroidism; pregnancy; survey; thyroid testing; screening; iodine; iodine deficiency; median urinary iodine concentration; Obstetrik och gynekologi; Obstetrics and Gynaecology;

   Sammanfattning : Hypothyroidism is a common endocrine disorder affecting women of reproductive age. On a global level, iodine deficiency is still the most common cause of hypothyroidism. Also genetic variations, in particular SNP rs4704397 in the PDE8B gene, are responsible for a significant proportion of TSH variations. LÄS MER