Sökning: "leukotriene B4"
Visar resultat 1 - 5 av 39 avhandlingar innehållade orden leukotriene B4.
1. Molecular Pharmacology and Structure Function Modelling of the Leukotriene B4 Receptor BLT1
Sammanfattning : Leukotrienes are membrane derived bioactive lipids that play an important role in immune responses by initiating and maintaining the inflammatory responses. Leukotriene B4 (LTB4) released at the site of an inflammatory response attracts, activates and prolongs the life of leukocytes and lymphocytes. LÄS MER
2. Biosynthesis of leukotriene B4 in hematological malignancies
Sammanfattning : Leukotrienes (LT) are biologically active metabolites of the fatty acid arachidonic acid (AA). After liberation of AA by phospholipase A 2 (PLA 2), this fatty acid can be converted to leukotrienes, lipoxins, prostaglandins or thromboxane. The conversion of AA to LTA 4 is catalyzed by five-lipoxygenase (5-LO). LÄS MER
3. Studies on leukotriene B4 and alarmins in inflammatory responses
Sammanfattning : Leukotriene B4 (LTB4) is a potent proinflammatory lipid mediator that is involved in host defense and inflammatory diseases, such as atherosclerosis. LL-37 and heparin binding protein (HBP) are cationic antimicrobial polypeptides, which belong to the alarmin family known to promote innate and adaptive immune reactions in response to tissue infection or injury. LÄS MER
4. Innate defense mechanisms of the nasal airway
Sammanfattning : Allergic and infectious rhinitis are prevalent conditions that besides a direct morbidity also causes exacerbations of asthma and chronic obstructive pulmonary disease. The immune mechanisms associated with various forms of rhinitis are not fully understood. LÄS MER
5. Intrafollicular pressure and biochemical mediators in ovulation
Sammanfattning : Ovulation is the process whereby the preovulatory follicle ruptures to enable a fertilisable ovum to escape from the interior of the ovary to the oviduct. During the ovulatory process, from he onset of the preovulatory LH-surge to the follicular rupture, marked biochemical and structural changes in follicles to enable it to rupture. LÄS MER