Sökning: "leukoplakia"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet leukoplakia.

  1. 1. Human Papilloma Virus, Epstein-Barr Virus, and Herpes Simplex Virus Type-1 in Oral Squamous Cell Carcinomas from Three Populations

    Författare :Jamshid Jalouli; Jan-Michaél Hirsch; Tina Dalianis; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HPV; EBV; HSV; Oral Squamous Cell Carcinoma; Leukoplakia; Oral Lichen Planus; Oral Submucuos Fibrosis; Toombak; Betel quid; Snuff; Oncology; Onkologi; Oncology; Onkologi;

    Sammanfattning : Most oral squamous cell carcinoma (OSCC) is believed to develop via a multistep process of cumulative gene damage in epithelial cells. Increasing incidence of OSCC and evidence that traditional risk factors may not be responsible directed us to investigate the prevalence of virus in pre- and malignant samples. LÄS MER

  2. 2. Oral cancer with special reference to virus detection and quantitative gene expression

    Författare :Miranda Shojaeian Jalouli; Lars Sand; Jan Hirsch; Torbjörn Ramqvist; Uppsala universitet; []
    Nyckelord :HPV; EBV; HSV-1; Oral Squamous Cell Carcinoma; Leukoplakia; apopto-sis; cell cycle regulation; intermediate filament proteins.; Medicinsk genetik; Medical Genetics;

    Sammanfattning : Background. Head and neck cancers (HNC) are among the most common malignancies worldwide, and about 90–92% of oral neoplasias are oral squamous cell carcinomas (OSCC). Alcohol and tobacco consumption have been recognized as the main risk factors for OSCC development. LÄS MER

  3. 3. Potentially Malignant Disorders and Oral cancer -A study on Immunosurveillance

    Författare :Jenny Öhman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oral lichen planus; Leukoplakia; Oral cancer; Immunosurveillance; Solid organ transplantation; T cells; Langerhans cells;

    Sammanfattning : ABSTRACT The cancer immunosurveillance hypothesis postulates that the immune system can recognize cancer cell precursors and destroy those cells before a clinical manifestation occurs. During the last decades several groups have presented evidence of the influence and role of immune activation in oral squamous cell carcinoma (OSCC) patients; however, much less is known about the role of immune activation in potentially malignant oral disorders (PMOD). LÄS MER

  4. 4. Oral leukoplakia, human papillomavirus and cancer transformation : Factors related to human papillomavirus infection and cell proliferation

    Författare :Jonas Sundberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; potentially malignant oral disorders; HPV; recurrence;

    Sammanfattning : Oral leukoplakia (OL) is clinically diagnosed as a white oral lesion that cannot be scraped of or diagnosed as any other type of oral lesion. OL has the potential to transform into oral squamous cell carcinoma (OSCC). The gold standard treatment is a combination of surgical excision if possible, and surveillance. LÄS MER

  5. 5. Oral mucosal lesions, tobacco use and the long-term outcome in a Swedish population

    Författare :Ann Roosaar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Follow up; mortality; oral lichen; oral leukoplakia; smokeless tobacco; smoking; snus; oral cancer; population-based;

    Sammanfattning : The overall objectives of this thesis were to study the natural history for Oral Lichen (OLL), Oral Leukoplakia (OL) and Snus Induced Lesions (SIL) and to correlate cancer and mortality among users and non-users of Swedish moist snuff (snus). The population sub-sample comprised a historic cohort of 20,333 individuals, established in 1973-74. LÄS MER