Sökning: "leukemia inhibitory factor"

Visar resultat 11 - 15 av 20 avhandlingar innehållade orden leukemia inhibitory factor.

  1. 11. Molecular and functional studies on human embryo implantation : targets for infertility and fertility regulation

    Författare :Nageswara Rao Boggavarapu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: An estimated one in four couples globally suffers from infertility or fertility related issues and rate of global infertility is about 10-15%. Despite the best optimization of assisted reproductive technique the pregnancy rate is not more than 30%. LÄS MER

  3. 12. Levonorgestrel emergency contraception : effects on endometrial development and embryo implantation

    Författare :Chun-Xia Meng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Emergency contraception; levonorgestrel; endometrial receptivity markers; embryo implantation; first-trimester tissues;

    Sammanfattning : Background: The dialog between the developing embryo and receptive endometrium is under the control of ovarian steroids and numerous biomolecules, some of which have been suggested as markers of endometrial receptivity. Unintended pregnancies are common. The standard treatment with levonorgestrel (LNG, 1. LÄS MER

  4. 13. Immunoregulation by mononuclear phagocytes. Mechanisms and clinical implications

    Författare :Ana Romero; Göteborgs universitet; []
    Nyckelord :;

    Sammanfattning : The cytotoxic effector lymphocytes of the immune system, the natural killer (NK) cells and the CD8+ T lymphocytes (CTL), have been ascribed a pivotal role in defense against malignancy. However, the function of these cells is frequently compromised, in particular at sites of malignant cell expansion. LÄS MER

  5. 14. Identification and characterization of novel genetic and epigenetic factors required for normal and malignant hematopoiesis

    Författare :Yaser Heshmati; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Acute myeloid leukemia (AML) is a type of blood cancer, characterized by clonal expansion and loss of differentiation ability of myeloid progenitor cells leading to abnormal accumulation of immature myeloid cells (myeloblasts) in the bone marrow and peripheral blood. This thesis (study I to IV) focused on the identification and characterization of genes which are required for AML growth. LÄS MER

  7. 15. Concepts in DNA immunization overcoming viral diversity and enhancing plasmid immunogenicity

    Författare :Erik Rollman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :HIV; DNA-vaccine; gp 160; GM-CSF; HPV 16 L OBS I; MuLV; prime-boost;

    Sammanfattning : On April 23, 1984, the prominent scientist Robert Gallo held a historical press conference at the Department of Health and Human Services, Washington D.C., USA. He announced that his laboratory at the National Institutes of Health had over the last months isolated a retrovirus named Human T-cell Leukemia Virus type III (HTLV-III). LÄS MER