Sökning: "leukemi"

Visar resultat 1 - 5 av 61 avhandlingar innehållade ordet leukemi.

  1. 1. Modelling the evolution of treatment-induced resistance in Ph+ leukaemias

    Författare :Jonathan Lindström; Ran Friedman; Arne Traulsen; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chronic myeloid leukaemia; Stochastic modelling; Tyrosine kinase inhibitor; Drug resistance; Clonal evolution; Biomedical Sciences; Biomedicinsk vetenskap; Medicinsk kemi; Medical Chemistry;

    Sammanfattning : Targeted therapies are a mainstay of modern cancer treatments. Rather than harming rapidly dividing cells in general, targeted therapies work by directly interfering with oncogenic molecular pathways present in a tumour. Consequently, a targeted therapy typically has less severe side effects. LÄS MER

  2. 2. Machine Learning Based Analysis of DNA Methylation Patterns in Pediatric Acute Leukemia

    Författare :Christofer Bäcklin; Mats Gustafsson; Markus Ringnér; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer in the Nordic countries. Recent evidence indicate that DNA methylation (DNAm) play a central role in the development and progression of the disease. LÄS MER

  3. 3. Novel imaging technology and tools for biomarker detection in cancer

    Författare :Zahra El-Schich; Malmö högskola; []
    Nyckelord :Biomarkers; Kronisk lymfatisk leukemi; Early detection of cancer; Diagnosis; Leukemia; Lymphocytic; Chronic; B-Cell; Apoptosis; Digital holografi;

    Sammanfattning : Cancer is a leading cause of death worldwide. Normally the balance betweencell growth and cell death is strongly controlled. Chronic lymphocytic leukemiais an indolent disease that has a highly variable clinical course and is the mostcommon hematological malignancy amongst adults in the Western countries. LÄS MER

  4. 4. Targeting Nutrient Transporters in Acute Myeloid Leukemia

    Författare :Hannah Åbacka; Medicinsk strukturbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Akut myeloisk leukemi; Metabolism; Transportörer; GLUT1; GLUT4; CD36; AQP7; ASPL; Inhibitor; Glukos; Fettsyra; Glycerol; Acute myeloid leukemia; Metabolism; Transporter; GLUT1; GLUT4; CD36; AQP7; ASPL; Small-molecule inhibitor; Glucose; Fatty acid; Glycerol;

    Sammanfattning : .... LÄS MER

  5. 5. Botad - till vilket pris? : en studie över livskvalitet och kostnad vid konventionell behandling av akut myeloisk leukemi = [Cured - at what price?] : [a study on quality of life and costs in conventional treatment of acute myeloid leukaemia]

    Författare :Ann Marie Stalfelt; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER