Sökning: "leptin"

Visar resultat 6 - 10 av 143 avhandlingar innehållade ordet leptin.

  1. 6. The role of leptin in zebrafish (Danio rerio) : Novel insights into appetite regulation and reproduction

    Författare :Emmanouil Tsakoumis; Monika Schmitz; Tatjana Haitina; Åsa Wallén-Mackenzie; Ana Gómez Peris; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; zebrafish; leptin; appetite; GRN; brain; reproduction; oocyte maturation; ovulation; Biology with specialization in Comparative Physiology; Biologi med inriktning mot jämförande fysiologi;

    Sammanfattning : The hormone leptin is a peripheral metabolic signal and an important regulator of energy balance. In mammals, leptin acts on the appetite centers in the hypothalamus, causing anorexigenic functions by inhibiting food intake. It is also considered as a link between the nutritional status and the endocrine reproductive axis. LÄS MER

  3. 7. Genes implicated in the development of obesity and obesity-related disease

    Författare :Kajsa Lindell; Göteborgs universitet; []
    Nyckelord :obesity; adipose tissue; hypothalamus; leptin; leptin receptor; 5 untranslated region; hypertension; angiotensinogen; DNA microarray;

    Sammanfattning : Obesity is a major health problem because of its dramatic increase in prevalence and the association of obesity with type 2 diabetes, coronary heart disease, hypertension and stroke. Although mutations in certain genes have been shown to cause obesity, the molecular mechanisms underlying obesity and obesity-related disease are still largely unknown. LÄS MER

  4. 8. Leptin and the Intersection of Cardiovascular Disease, Metabolism, and Adipose Tissue

    Författare :Camilla Vavruch; Fredrik Nyström; Carl Johan Östgren; Johan Ärnlöv; Kristina Boström; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Leptin; Type 2 diabetes mellitus; Adipose tissue; Cardiovascular disease; Metabolism; Cardiovascular risk factors;

    Sammanfattning : According to the World Health Organization, cardiovascular disease (CVD) is a group of disorders of the heart and blood vessels, and it is the leading cause of death worldwide. The risk factors for CVD are divided into two major classes: non-modifiable (age, gender, family history) and modifiable (including tobacco use, type 2 diabetes mellitus (T2DM), physical inactivity, unhealthy diet, abdominal obesity, high cholesterol, dyslipidemia, and stress). LÄS MER

  5. 9. Effects of palatable diets on appetite regulation, appetite peptides and neurogenesis

    Författare :Andreas Lindqvist; Aptitkontroll; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sekretion; Endokrinologi; diabetologi; Appetite regulation; Ghrelin; Obesity; Leptin; Endocrinology; diabetology; secreting systems;

    Sammanfattning : Obesity is increasing throughout the world at an epidemic rate, partly due to increased consumption of diets rich in fat and/or sugar. Ghrelin and leptin are hormones, originating from the periphery, involved in the regulation of food intake and of maintaining energy homeostasis. LÄS MER

  7. 10. Trends in obesity and type 2 diabetes : ethnic aspects and links to adipokines

    Författare :Mikael Lilja; Stefan Söderberg; Olov Rolandsson; Mats Eliasson; Kurt Svärdsudd; Umeå universitet; []
    Nyckelord :Type 2 diabetes; leptin; adiponectin; obesity; abdominal obesity; epidemiology; ethnicity; fasting glucose; post-load glucose; Family Medicine; allmänmedicin;

    Sammanfattning : Objective The prevalence of obesity and related diseases such as type 2 diabetes mellitus (T2DM) is increasing worldwide, and the Asian Indian population seems to be particularly susceptible to developing T2DM, even at a low body mass index (BMI). In Sweden, the age-adjusted prevalence of diabetes has not increased despite increasing self-reported obesity. LÄS MER