Sökning: "latent tuberculosis infection"

Visar resultat 1 - 5 av 19 avhandlingar innehållade orden latent tuberculosis infection.

  1. 1. Tuberculosis infection in pregnant women

    Författare :John Walles; Klinisk infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tuberculosis; Pregnancy; Latent; stillbirth; preeclampsia; QuantiFERON;

    Sammanfattning : .... LÄS MER

  3. 2. Dynamics of tuberculosis infection in Sweden

    Författare :Niclas Winqvist; Enheten för infektionssjukdomar; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tuberculosis; latent tuberculosis infection; long-term follow-up; Øresund region; interferon-gamma release assay; tuberculin skin test;

    Sammanfattning : Sweden provides a special setting for epidemiological and demographic studies of tuberculosis (TB) infection over time for principally two reasons; first, the Swedish TB epidemic has undergone a tremendous transition since the end of the 19th century, when TB was highly endemic, to the current situation with practically interrupted indigenous transmission since several decades. Second, an increasing proportion of persons who grew up before TB transmission virtually disappeared in the 1960s are reaching advanced age, and thus creating conditions that predispose to reactivation of latent TB infection (LTBI). LÄS MER

  4. 3. Immunological aspects of latent tuberculosis infection during pregnancy

    Författare :Fregenet Tesfaye Tegegn; Klinisk infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Interferon-γ; immune mediators; latent tuberculosis infection; Mtb-antigen reactivity; pregnancy; QuantiFERON-TB Gold Plus;

    Sammanfattning : Pregnancy-induced immune modulation might lead to reactivation of latent tuberculosis infection (LTBI). This thesis explores aspects of immune-based LTBI diagnostics and how pregnancy affects the immune control of Mycobacterium tuberculosis (Mtb) infection. We studied a prospective cohort of women recruited during pregnancy in Ethiopia. LÄS MER

  5. 4. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    Författare :Johanna Raffetseder; Maria Lerm; Olle Stendahl; Vesa Loitto; Trude Helen Flo; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Sammanfattning : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. LÄS MER

  7. 5. Immune responses against Mycobacterium tuberculosis targets associated to latent and active tuberculosis infection

    Författare :Nancy Montserrat Alvarez-Corrales; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Tuberculosis is a worldwide problem particularly in developing countries. Different clinical outcomes, such as the asymptomatic phase during infection or the symptomatic stage during active disease leads to activation and expansion of cellular immune responses in order to control the infection. LÄS MER