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Hittade 5 avhandlingar som matchar ovanstående sökkriterier.

1. 1. A study on the vascular effects of prostaglandin F2α[ and latanaprost in the eye with special reference to the surface hyperaemia after topical administration

   Författare :Maria Astin; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Prostaglandin F2a; Prostaglandin F2a-isopropyl ester; latanoprost; latanoprost acid; ocularhyperaemia; blood flow; sensory nerves; veins; arteries; nitric oxide; substance P; CGRP; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; Pharmacognosy; farmakognosi;

   Sammanfattning : The ocular hypotensive effect of topically applied prostaglandins is usually accompanied byconjunctival hyperaemia and irritation. The purpose of the present study was to investigate thepharmacological mechanism of the ocular surface hyperaemia induced by topically appliedprostaglandins, particularly prostaglandin F2α (PGF2α) and its synthetic analogue latanoprost, aselective FP prostanoid receptor agonist. LÄS MER

3. 2. Pooling Data from Similar Randomized Clinical Trials Comparing Latanoprost with Timolol; Medical Results and Statistical Aspects

   Författare :Katarina Hedman; Albert Alm; Adam Taube; T Joseph Sheehan; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ophtalmology; mean intraocular pressure; target intraocular pressure; latanoprost; timolol; open-angle glaucoma; ocular hypertension; trial design; Oftalmiatrik; Ophtalmology; Oftalmologi; Ophtalmology; oftalmiatrik;

   Sammanfattning : Two different principles were studied. 1st - statistical analysis techniques were used to obtain medical results from a patient population. 2nd - the patient population was used to study the statistical analysis techniques. LÄS MER

4. 3. Aspects on prostanoid and cholinergic effects on aqueous humour dynamics in human eyes

   Författare :Christina Lindén; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Aqueous flow; blood-aqueous barrier; flare; human; intraocular pressure IOP ; latanoprost; physostigmine; prostaglandins; uveoscleral flow;

   Sammanfattning : The discovery of the ocular hypotensive effect of topically applied prostaglandins (PGs) has raised a number of questions about the mechanisms of action involved. The aim of the present thesis was to answer some of these questions. LÄS MER

5. 4. The prostanoid FP receptor and uveoscleral outflow : A study of FP receptor expression and functions in the eye

   Författare :Anette Ocklind; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Prostanoid FP receptor; tissue distribution; ciliary muscle; iris sphincter muscle; extracellularmatrix; actin; prostaglandin F2a; latanoprost; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

   Sammanfattning : Prostaglandin F2α is a prostanoid FP receptor agonist which acts as an intraocular pressure-lowering agent by increasing the uveoscleral outflow of aqueous humour through the ciliary muscle. The aim of this, thesis was to investigate possible mechanisms of the increased uveoscleral outflow induced by prostaglandin F2α and its analogue latanoprost acid. LÄS MER

7. 5. Aspects of the diagnosis and treatment of glaucoma

   Författare :Björn Friström; Linköpings universitet; []
   Nyckelord :MEDICINE; MEDICIN;

   Sammanfattning : Glaucoma is one of the most common causes of blindness in the world, and it is important that screening tests as well as treatment possibilities are improved continuously. A reliable but more rapid screening test than those already available would be of great interest. In addition, new and more effective treatment options would be most valuable. LÄS MER