Sökning: "lac operon"

Hittade 2 avhandlingar innehållade orden lac operon.

1. 1. Orientational dynamics of single molecules applied to protein-DNA target search

   Författare :Emil Marklund; Johan Elf; Erwin Peterman; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; single molecule imaging; fluorescence correlation spectroscopy; gene regulation; transcription factor; lac operon;

   Sammanfattning : Cells in all life forms regulate their genes with the help of transcription factors (TFs). These proteins turn genes on or off by binding regulatory motifs present in the DNA. Before this binding can occur, a TF needs to search and find the specific binding site in the genome of the cell. LÄS MER

3. 2. lac of Time : Transcription Factor Kinetics in Living Cells

   Författare :Petter Hammar; Johan Elf; Antoine van Oijen; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; gene regulation; transcription factor; lac operon; facilitated diffusion; single molecule imaging; Molecular Biotechnology; Molekylär bioteknik;

   Sammanfattning : Gene regulation mediated by transcription factors (TFs) is essential for all organisms. The functionality of TFs can largely be described by the fraction of time they occupy their regulatory binding sites on the chromosome. DNA-binding proteins have been shown to find their targets through facilitated diffusion in vitro. LÄS MER