Sökning: "label-free cell separation"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden label-free cell separation.

1. 1. Label-free processing of stem cell preparations by acoustophoresis

   Författare :Franziska Olm; Avdelningen för molekylär hematologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acoustophoresis; label-free cell separation; ultrasound; microfluidics; stem cell processing; CTC separation;

   Sammanfattning : The first bone marrow transplant in a human was performed in 1959, providing evidence that cells can be used for transplantation and treatment, revealing that healing capacities lie within the human body that ought to be understood. Since then hematopoietic stem cell transplantation has developed as a standard treatment for many cancers besides other malignancies. LÄS MER

3. 2. Quality Control for high-throughput Quantitative Proteomics - Harnessing the potential of label-free LC-MS

   Författare :Marianne Sandin; Institutionen för immunteknologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proteomics; mass spectrometry; quality control; data analysis; label-free; feature detection; alignment; biomarker discovery; separation techniques;

   Sammanfattning : Multiplex protein quantification, proteomics, is essential for uncovering new biomarkers and understanding biology. Liquid chromatography coupled to mass spectrometry (LC-MS) is the predominant technique for these measurements. LÄS MER

4. 3. Deterministic Lateral Displacement for Cell Separation

   Författare :Si Hoai Trung Tran; NanoLund: Centre for Nanoscience; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Deterministic lateral displacement; Cell Separation; Open microfluidics;

   Sammanfattning : In the fields of medicine and biology, the separation of particles is a central step in many preparative and analytical processes. Deterministic Lateral Displacement (DLD) has been a promising technique in the field of microfluidic particle and cell sorting, specifically for label-free separation with several applications of sorting by size, morphology, and deformation reported in the literature over the last decade. LÄS MER

5. 4. Cell Sorting in Pillar Arrays based on Electrokinetics and Morphology

   Författare :Bao Dang Ho; NanoLund: Centre for Nanoscience; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell Sorting; Label-Free Separation; Deterministic Lateral Displacement; Electrokinetics; Fysicumarkivet A:2018:Dang Ho;

   Sammanfattning : Deterministic Lateral Displacement (DLD) is a method capable of sorting cells based on size where mechanicalinteractions between a sufficiently large particle and obstacles in a microfludic pillar array force the particle tofollow a different trajectory than their smaller counterparts, resulting in continuous lateral separation. To extendthe capability of DLD, electrical interaction between particles and pillars can be employed to complement themechanical interaction, making electrical/dielectric properties additional parameters for sorting. LÄS MER

7. 5. Applications of hydrodynamic forces for membrane chromatography

   Författare :Björn Johansson Fast; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane chromatography; FRAP; Protein accumulation; Supported lipid bilayer; Microfluidics; SEEC; Diffusion; Hydrodynamic forces; Label-free;

   Sammanfattning : Membrane proteins are proteins that reside in the cell membrane. Due to their position in the cell membrane, the barrier between the cell interior and exterior, they are vital to cell signaling. Moreover, the presence of membrane proteins in the cell's signaling pathways make membrane proteins important drug targets. LÄS MER