Sökning: "lab-on-chip"

Visar resultat 6 - 10 av 16 avhandlingar innehållade ordet lab-on-chip.

  1. 6. Development of materials, surfaces and manufacturing methods for microfluidic applications

    Författare :Carl Fredrik Carlborg; Wouter van der Wijngaart; Shoji Takeuchi; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; microsystem technology; MEMS; microfluidics; polymers; off-stoichiometry thiol-ene; point-of-care; lab-on-chip; Electrical engineering; electronics and photonics; Elektroteknik; elektronik och fotonik;

    Sammanfattning : This thesis presents technological advancements in microfluidics. The overall goals of the work are to develop new miniaturized tests for point-of-care diagnostics and robust super-lubricating surfaces for friction reduction. To achieve these goals, novel materials, surfaces and manufacturing methods in microfluidics have been developed. LÄS MER

  3. 7. Microfluidic blood sample preparation for rapid sepsis diagnostics

    Författare :Jonas Hansson; Hjalmar Brismar; Aman Russom; Fredrik Nikolajeff; KTH; []
    Nyckelord :3D fluidic networks; bacteria isolation; inertial microfluidics; lab-on-chip; microfluidics; particle filtration; PDMS membrane; selective cell lysis. sepsis;

    Sammanfattning : Sepsis, commonly referred to as blood poisoning, is a serious medical condition characterized by a whole-body inflammatory state caused by microbial infection. Rapid treatment is crucial, however, traditional culture-based diagnostics usually takes 2-5 days. LÄS MER

  4. 8. Single Molecule Detection : Microfluidic Automation and Digital Quantification

    Författare :Malte Kühnemund; Mats Nilsson; Ulf Landegren; Sten Linnarsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; single molecule; digital; rolling circle amplification; magnetic particle; padlock probe; microfluidics; resistive pulse sensing; lab on chip; mobile phone microscopy; enrichment; sequencing;

    Sammanfattning : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. LÄS MER

  5. 9. Microfluidics in Surface Modified PDMS : Towards Miniaturized Diagnostic Tools

    Författare :Sara Thorslund; Fredrik Nikolajeff; Jonas Bergquist; Elisabeth Verpoorte; Uppsala universitet; []
    Nyckelord :Materials science; µTAS; micro total analysis system; PDMS; poly dimethylsiloxane ; microfluidics; heparin; blood filtration; on-chip; ESI-MS; desalting; QCM-D; biocompatible; CD4; capillary flow; lab-on-chip; microfabrication; enrichment; point-of-care; hydrophilic; oxidation; Materialvetenskap;

    Sammanfattning : There is a strong trend in fabricating miniaturized total analytical systems, µTAS, for various biochemical and cell biology applications. These miniaturized systems could e.g. gain better separation performances, be faster, consume less expensive reagents and be used for studies that are difficult to access in the macro world. LÄS MER

  7. 10. OSTE Microfluidic Technologies for Cell Encapsulation and Biomolecular Analysis

    Författare :Xiamo Zhou; Wouter van der Wijngaart; Ellis Meng; KTH; []
    Nyckelord :Microfluidics; microfabrication; cell encapsulation; core-shell particle; microparticle synthesis; off-stoichiometry-thiol-ene; OSTE; OSTE ; lab-on-a-chip; surface modification; core-shell particle co-synthesis; microar- ray; micromixer; bonding; surface modification; droplet microfluidics; protein screening.; Mikrofluidik; mikrofabrikation; cellinkapsling; cores-shell kap- sel; mikrokapselsyntes; lab-on-chip; ickestökiometrisk tiol-en; OSTE; OSTE ; ytmodifiering; samtidig syntes av core-shellkapslar; mikroarray; mikromixer; sammanfogning; dropletmikrofluidik; proteindetektion.; Tillämpad medicinsk teknik; Applied Medical Technology;

    Sammanfattning : In novel drug delivery system, the encapsulation of therapeutic cells in microparticles has great promises for the treatment of a range of health con- ditions. Therefore, the encapsulation material and technology are of great importance to the validity and efficiency of the advanced medical therapy. LÄS MER