Sökning: "l cancer"

Visar resultat 1 - 5 av 139 avhandlingar innehållade orden l cancer.

  1. 1. Targeted therapeutic strategies for prostate cancer treatment using novel lipid kinase inhibitors in combination with current drugs

    Författare :Julius Semenas; Jenny L. Persson; Anna Berghard; Maria Fällman; Thomas Grundström; Lukas Kenner; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; bone metastasis; castration-resistant; treatment; precision therapy; PIP5K1A; steroid hormone receptors; cancer stem cells; Oncology; onkologi;

    Sammanfattning : Prostate cancer (PCa) is one of the most common cancer types and the fifth cancer-related cause of death among Western world men.  The sex steroid hormone, androgen and androgen receptor (AR) play important roles in PCa progression. LÄS MER

  3. 2. Cancer Immunotherapy : A Preclinical Study of Urinary Bladder Cancer

    Författare :Christina Ninalga; Thomas Tötterman; Magnus Essand; Timothy Ratliff; Uppsala universitet; []
    Nyckelord :Medicine; immunotherapy; bladder carcinoma; cancer; CpG ODNs; Adenoviral vector; CD40L; TRANCE; Lymphotactin; IL2; IL15; Medicin;

    Sammanfattning : Bacillus Calmette Guérin (BCG), or attenuated Mycobacterium bovis, is the gold standard of immunotherapy in the clinic to treat superficial bladder cancer. However, setbacks remain due to a high recurrence rate, side effects, and BCG-refractory disease. LÄS MER

  4. 3. Mismatch repair deficiency in colorectal cancer : prognosis and prediction for basic treatment strategies

    Författare :Ioannis Gkekas; Jan Novotny; Karin Strigård; Richard Palmqvist; Ulf Gunnarsson; Christian Sturesson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; defective mismatch repair; prognosis and prediction; Oncology; onkologi;

    Sammanfattning : Colorectal cancer (CRC) remains a significant healthcare problem worldwide, being the third most common cancer and the fourth most frequent cause of cancer death. Environmental and dietary factors such as alcohol abuse, cigarette smoking, and genetic predisposition seem to constitute the main aetiologies. LÄS MER

  5. 4. LRIG1 in lung cancer : prognostic effects and mechanistic studies

    Författare :Samuel Kvarnbrink; Mikael Johansson; Håkan Hedman; Odd Terje Brustugun; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; lung cancer; metastasis; prognosis; LRIG1; LRIG3; LMO7; LIMCH1; Oncology; onkologi;

    Sammanfattning : Lung cancer is the leading cause of cancer-related death worldwide as well as in Sweden. Non-small cell lung cancer (NSCLC) is the predominant form, which is largely subdivided into adenocarcinomas and squamous cell carcinomas. LÄS MER

  7. 5. Esophageal- and Gastroesophageal Junctional Cancer : Aspects on Staging, Treatment and Results

    Författare :Gustav Linder; Jakob Hedberg; Magnus Sundbom; Wilhelm Graf; Bas P.L. Wijnhoven; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Esophageal cancer; Education level; Tonometry; Lymphadenectomy; PET MRI; Kirurgi; Surgery;

    Sammanfattning : Esophageal- and gastroesophageal junctional (GEJ) cancer is the sixth cause of cancer-related death worldwide. Some improvements in care are attributed to nationwide disease-specific registries, preoperative staging and increased understanding of mechanisms affecting patient selection. LÄS MER