Sökning: "läkemedel utveckling"

Visar resultat 1 - 5 av 120 avhandlingar innehållade orden läkemedel utveckling.

  1. 1. Selective serotonin re-uptake inhibitors in the environment : Effects of citalopram on fish behaviour

    Författare :Martin Kellner; Håkan Olsén; Inger Porsch-Hällström; Magnus Breitholtz; Södertörns högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Citalopram; SSRI; stickleback; Baltic; behaviour; fish; feeding; anxiety; boldness; serotonin; development; Storspigg; serotonin; östersjön; SSRI; läkemedel; miljö; citalopram; ätbeteende; beteende; utveckling; Environmental Studies; Miljövetenskapliga studier; Östersjö- och Östeuropaforskning; Baltic and East European studies;

    Sammanfattning : Selective serotonin re-uptake inhibitors (SSRIs) are a class of anxiolytic and anti-depressant drugs. SSRIs act on the evolutionarily ancient serotonergic system which is virtually identical throughout the vertebrate phylum. LÄS MER

  3. 2. Design strategies for new drugs targeting multicomponent systems : focusing on class II MHC proteins and acetylcholinesterase

    Författare :Cecilia Lindgren; Anna Linusson; Antti Poso; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; acetylcholinesterase; class II MHC protein; drug design; molecular dynamics simulation; multicomponent system; nerve agent; oxime; quantitative structure-activity relationship; reactivator; rheumatoid arthritis; statistical molecular design; T-cell receptor;

    Sammanfattning : The field of medicinal chemistry is constantly evolving. Aided by advances within techniques as well as knowledge of biological systems, increasingly complex targets and drugs can be considered. LÄS MER

  4. 3. Change in the Pharmaceutical Industry : Aspects on Innovation, Entrepreneurship, Openness, and Decision Making

    Författare :Thomas Hedner; Magnus Klofsten; Johan Braet; Mirjam Knockaert; Linköpings universitet; []
    Nyckelord :Pharmaceutical industry; Big Pharma; life sciences; drug discovery; drug development; R D; business model; innovation; closed innovation; open innovation; entrepreneurship; intellectual property; multiple stakeholders; decision making; judgment; uncertainty; go no-go; go no-go recycle; company; SME.; Läkemedelsindustri; Big Pharma; biovetenskap; läkemedelsutveckling; utveckling av läkemedel; FoU; affärsmodell; innovation; stängd innovation; öppen innovation; entreprenörskap; immaterialrätt; beslutsfattande; osäkerhet; go no-go; go no-go recycle; företag; små och medelstora företag;

    Sammanfattning : Over the past century, the pharmaceutical industry has been a major contributor of individual and population health and societal wealth. Its products and services have contributed to longevity of large groups of patients and symptom relief from major diseases. LÄS MER

  5. 4. Fat bloom on chocolate confectionery systems - From core to surface

    Författare :Hanna Dahlenborg; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; surface structure; particles; migration; fat bloom; cocoa butter; chocolate;

    Sammanfattning : Abstract Fat bloom on chocolate is a major problem for the confectionery industry since the unappetising appearance and negative sensory effects lead to rejection by customers. The presence of fat bloom on chocolate confectionery systems is usually connected to migration of liquid fat due to the difference in composition between filling triacylglycerols (TAGs) and cocoa butter TAGs. LÄS MER

  7. 5. Mass transport mechanisms and module design aspects in the recovery of dilute volatile organic compounds by hydrophobic pervaporation

    Författare :Olivera Trifunovic; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Livsmedelsteknik; Food and drink technology; Teknik; Technological sciences; Aroma recovery; Module design; Hydrophobic pervaporation; Mass transport;

    Sammanfattning : Hydrophobic pervaporation has gained a lot of attention as an alternative process for mild aroma recovery, but the real commercial applications of this process are still in their infancies. Better understanding of mass transport phenomena in composite pervaporation membranes is essential from the point of view of membrane manufacturing, while process simulation is an important tool for predicting pervaporation module performance. LÄS MER