Sökning: "kroniska sjukdom"
Visar resultat 1 - 5 av 58 avhandlingar innehållade orden kroniska sjukdom.
1. WOMEN WITH IRRITABLE BOWEL SYNDROME. Aspects of quality of life and health
Sammanfattning : Irritable Bowel Syndrome (IBS) is a common, worldwide, functional disorder affecting a significant number of people, predominantly women. Etiology and pathophysiology is insufficiently understood, but the research over the past decade has led to progress in the understanding of IBS, and it is generally accepted that the symptoms of IBS are multidetermined. LÄS MER
2. Upper gastrointestinal dysmotility - from endocrinological pathogenesis to symptoms
Sammanfattning : Gastrointestinal dysmotility is common, particularly in patients with diabetes mellitus. The aim of this thesis is to explore whether gastrointestinal dysmotility and endocrine secretion are interrelated, and how the symptoms manifest themselves in these patients. LÄS MER
3. On the regulation and effects of chronic inflammation in inflammatory bowel disease
Sammanfattning : Inflammatory bowel disease is thought to result from the inappropriate and ongoing activation of the mucosal immune system driven by the presence of normal luminal flora. In this process monocytes/macrophages contribute to and maintain chronic inflammation by being both regulatory and effector cells. LÄS MER
4. Endogenous proteins as markers of glomerular function and dysfunction
Sammanfattning : Plasma and urine concentrations of endogenous proteins are frequently used in the diagnosis of kidney diseases and in studies of glomerular filter function. The main issues addressed in these studies were: storage of urine samples for subsequent protein analysis, use of protein concentrations in urine and in plasma in health and as markers of glomerular diseases, and the application of renal plasma-to-urine clearance of endogenous proteins in estimating the size-selectivity properties of the glomerular capillary wall. LÄS MER
5. GDNF gene delivery in an animal model of Parkinson's disease. Long-term effects on intact, injured and transplanted dopamine neurons using lentiviral gene transfer
Sammanfattning : Parkinson's disease is characterized by a progressive degeneration of dopaminergic neurons in the substantia nigra, leading to a loss of dopamine in the target structure striatum and development of motor symptoms, such as bradykinesia, rigidity and tremor. New experimental treatment strategies for Parkinson's disease are aimed at either preventing the degeneration of the dopaminergic neurons, or at restoring dopamine in the striatum by fetal dopaminergic transplants. LÄS MER