Sökning: "kromosom analys"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden kromosom analys.

  1. 1. Molecular Characterization of Genomic Amplifications in Pancreatic Cancer

    Författare :Markus Heidenblad; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FISH; Clinical genetics; PCR; cDNA microarray; array-based CGH; expression profiling; genomic profiling; Pancreatic cancer; gene amplification; Klinisk genetik;

    Sammanfattning : Pancreatic cancer includes multiple histologic subtypes that show large differences in their clinical and biological characteristics. Despite this diversity, more than 85% of the neoplasms in the organ are malignant ductal adenocarcinomas, which are the focus of the present thesis. LÄS MER

  3. 2. Genetic Analysis of Cytosolic PGI in Festuca ovina

    Författare :Lena Ghatnekar; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Växtgenetik; Plant genetics; pseudogenes; grasses; cytosolic PGI; introgression; duplication; Festuca ovina;

    Sammanfattning : Festuca ovina, sheep's fescue is a widely distributed perennial outbreeder that belongs to the grass family Poaceae and is very common in the northern temperate zone. The genus Festuca s.l. is partitioned into fine-leaved fescues to which F. LÄS MER

  4. 3. Population-based prediction of atrial fibrillation

    Författare :Gustav Smith; Kardiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; atrial fibrillation; prediction; epidemiology; genetics; natriuretic peptide; heart failure;

    Sammanfattning : Background: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and increases in prevalence. As AF confers increased risk of morbidity, stroke, dementia and mortality, a major objective of cardiovascular epidemiology today is the development of tools for prediction and prevention of AF and its consequences. LÄS MER

  5. 4. Characterization of somatic mutations in nonneoplastic cells

    Författare :Karin Broberg; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical genetics; osteoarthritis; nonneoplastic; HMGIC; trisomy 7; FISH; Molecular genetics; cytogenetics; Klinisk genetik;

    Sammanfattning : Acquired genetic alterations, of which many are visible on the chromosome level, are believed to be necessary for tumorigenesis, and most tumors display characteristic patterns of recurrent structural and numerical aberrations. However, two of the most frequently occurring chromosome mutations in malignant and benign solid tumors, i.e. LÄS MER

  7. 5. Genetic and molecular alterations in aldosterone producing adenomas

    Författare :Ravi Kumar Dutta; Peter Söderkvist; Oliver Gimm; Ute Scholl; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Aldosterone producing tumors (APA, also known as Conn tumors) are adrenal tumors that overproduce aldosterone, a hormone that regulates the sodium levels in blood and contributes to blood pressure (BP) regulation. Excessive production of aldosterone causes hypertension and approximately 5-15% of hypertensive patients have hyperaldosteronism, known as primary aldosteronism (PA). LÄS MER