Sökning: "known and"

Visar resultat 16 - 20 av 9157 avhandlingar innehållade orden known and.

  1. 16. Sex differences in immune response and sex hormone receptor expression in healthy individuals and during viral infection

    Författare :Peik M. A. Brundin; Anders F. Johansson; Ivan Nalvarte; Carl-Johan Treutiger; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; immune response; menstrual cycle; puumala virus; hantavirus; torque teno virus; sex hormones; sex hormone receptors; estrogen receptors; estrogen receptor beta2; sex differences; microbiome; virome; endocrinology; peripheral blood mononuclear cells; qPCR; Infectious Diseases; infektionssjukdomar; medicinsk virologi; Medical Virology; immunologi; Immunology; Medical Cell Biology; medicinsk cellbiologi; molekylärbiologi; Molecular Biology; Medicine; medicin; obstetrik och gynekologi; Obstetrics and Gynaecology;

    Sammanfattning : There is sex-bias in morbidity and mortality from infectious diseases. Infections kill more men than women and several studies have pointed out differences in the immune system as a reason. The sex hormones estrogen, progesterone and testosterone all shape the effect of the immune response on multiple levels. LÄS MER

  3. 17. Vulnerabilities and Resources : Exploring intersecting conditions for health equity in sexual and reproductive health and rights(SRHR) among young people in Sweden

    Författare :Anna ChuChu Schindele; Malin Lindroth; Kristina Areskoug Josefsson; Emma Sorbring; Malmö universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Health and society; Hälsa och samhälle;

    Sammanfattning : SVENSK SAMMANFATTNINGBAKGRUND: Sexuell och reproduktiv hälsa och rättigheter (SRHR) är en central bestämningsfaktor för hälsa och utgör en viktig del av livet i övergången från barndom till vuxen ålder. Den nationella SRHR-policyn i Sverige strävar mot jämlika förutsättningar för hälsa. LÄS MER

  4. 18. Alcohol and aging : a multimethod study on heterogeneity and multidimensionality

    Författare :Wossenseged Birhane Jemberie; Mojgan Padyab; Fredrik Snellman; Malin Eriksson; Neda Agahi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; older adults; substance use disorder; alcohol use disorder; comorbidity; recovery; alcohol treatment; aging; healthy aging; integrated care; person-centered care; biopsychosocial model; register-based; longitudinal; latent class; medical behavioral science; medicinsk beteendevetenskap; health services research; hälso- och sjukvårdsforskning; health services research; hälso- och sjukvårdsforskning; psykiatri; Psychiatry;

    Sammanfattning : Background and Objectives: With an ageing population, the number of older persons with substance use problems, particularly problematic alcohol use, is increasing. Despite grow­ing recognition of the negative consequences of problematic alcohol use on older persons, there is a dearth of knowledge about the alcohol use profiles and the dimensionality of alcohol problems in older people. LÄS MER

  5. 19. Integrating Efficacy and Toxicity in Preclinical Anticancer Drug Development : Methods and Applications

    Författare :Caroline Haglund; Elin Lindhagen; Rolf Larsson; Anna Åleskog; Sigurd Vitols; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anticancer drugs; In vitro assays; Toxicity testing; Haematological toxicity; Primary tumour cells; Species difference; Clinical pharmacology; Klinisk farmakologi; Clinical Pharmacology; Klinisk farmakologi;

    Sammanfattning : Preclinical testing is an important part of cancer drug development. The aim of this thesis was to establish and evaluate preclinical in vitro methods useful in the development of new anticancer drugs. In paper I, the development of non-clonogenic assays (FMCA-GM) using CD34+ stem cells for assessment of haematological toxicity was described. LÄS MER

  7. 20. Rotavirus Disease Mechanisms Diarrhea, Vomiting and Inflammation : How and Why

    Författare :Marie Hagbom; Lennart Svensson; Karl-Eric Mangusson; Ove Lundgren; Niklas Arnberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Rotavirus infections cause diarrhea and vomiting that can lead to severe dehydration. Despite extensive tissue damage and cell death, the inflammatory response is very limited. LÄS MER