Sökning: "known and"

Visar resultat 1 - 5 av 7745 avhandlingar innehållade orden known and.

  1. 1. Walking the Plank of the Entrepreneurial University The little spin-out that could?

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Nina Fowler; David Sköld; Marcus Lindahl; Malin Brännback; [2017]
    Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; University spinouts; research; academic capitalism; entrepreneurship; commercialisation; social forces; Engineering Science with specialization in industrial engineering and management; Teknisk fysik med inriktning mot industriell teknik;

    Sammanfattning : Creating spinout companies (USOs) from university research is one focus of innovation policy. The phenomenon features in two main fields of enquiry: academic entrepreneurship studies, and literature on academic capitalism and the entrepreneurial university. LÄS MER

  2. 2. Free energy calculations of G protein-coupled receptor modulation New methods and applications

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Willem Jespers; Hugo Gutiérrez-de-Terán; Johan Åqvist; Jonathan Essex; [2020]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; G protein-coupled receptor; adenosine receptor; molecular dynamics; free energy perturbation; homology modeling; computer simulations; conformational selectivity; binding free energy.; Biology with specialization in Molecular Biotechnology; Biologi med inriktning mot molekylär bioteknik;

    Sammanfattning : G protein-coupled receptors (GPCRs) are membrane proteins that transduce the signals of extracellular ligands, such as hormones, neurotransmitters and metabolites, through an intracellular response via G proteins. They are abundant in human physiology and approximately 34% of the marketed drugs target a GPCR. LÄS MER

  3. 3. Heparan sulfate dependent cell signaling and associated pathophysiology Implications in tumorigenesis and embryogenesis

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Tahira Batool; Jin-Ping Li; Aristidis Moustakas; Liliana Schaefer; Ingvar Ferby; Michael Welsh; Anders Malmström; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparanase; Glucuronyl-C5 epimerase; Heparan Sulfate; Heparin; Lung Cancer; Cancer cell Singling; TGF-Beta; BMP; VEGF; Notch Signaling; Tumor growth; Metastasis; embryonic development; Medical Biochemistry; Medicinsk biokemi;

    Sammanfattning : Heparan sulfate proteoglycans (HSPGs) consist of a protein core to which several linear, negatively charged heparan sulfate (HS) chains are covalently attached. HSPGs are expressed on the cell surface and in the extra-cellular matrix (ECM) where they have diverse biological functions, for example co-receptor functions. LÄS MER

  4. 4. Tumour evolution and novel biomarkers in breast cancer

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jana Biermann; Göteborgs universitet.; Gothenburg University.; Göteborgs universitet.; Gothenburg University.; [2019]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; gene signature; molecular biomarkers; tumour clonality; genomic instability; Swedish haemangioma cohort;

    Sammanfattning : Several gene signatures have been proposed in the past two decades to improve outcome prediction for breast cancer patients and to guide treatment decisions. Current treatment guidelines, however, primarily focus on established clinicopathological features. LÄS MER

  5. 5. Shear Fracture and Delamination in Packaging Materials A study of Experimental Methods and Simulation Techniques

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Md. Shafiqul Islam; Sharon Kao-Walter; Christian Johansson; Johan Tryding; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Package opening; Shear test specimen; Stress intensity factor; Finite Element simulation; Scanning electron microscopy; Polymers; Interlaminar shear delamination;

    Sammanfattning : Packages are the means of preservation, distribution and convenience of use for food, medicine and other consumer products. Package opening is becoming complicated in many cases because of cutting cost in design and production of opening techniques. LÄS MER