Sökning: "kinin system"

Visar resultat 1 - 5 av 12 avhandlingar innehållade orden kinin system.

  1. 1. Kinin System Activation in Vasculitis

    Författare :Robin Kahn; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kinin receptors; inflammation; vasculitis; proteinase 3; neutophils; anti-neutrophil-cytoplasmic antibodies; Kinin;

    Sammanfattning : The kinin system is activated when high-molecular-weight kininogen (HK) is cleaved by plasma kallikrein thus generating bradykinin. Bradykinin is a potent proinflammatory peptide that induces plasma leakage, blood pressure drop, liberation of inflammatory cytokines and pain. LÄS MER

  3. 2. The kallikrein-kinin system in primary hypertension : dynamics of circulating components of the kallikrein-kinin system in relation to the renin-angiotensin-aldosterone system

    Författare :K. Peter Öhman; Linköpings universitet; []
    Nyckelord :aldosterone; angiotensin Il; blood pressure; human; prekallikrein; renin; tissue kallikrein; MEDICINE; MEDICIN;

    Sammanfattning : Kinins are potent vasodilatory and blood pressure lowering peptides, with additional effects on renal handling of electrolytes and water. The kallikrein-kinin system consists of two separate entities, one confined to the circulation and the other to both tissues and the circulation. LÄS MER

  4. 3. Inflammation, kinins, and kinin receptors

    Författare :Sara Bengtson; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Evidence is accumulating that the pathogenesis of many diseases is triggered by inappropriate inflammatory responses. These serious complications may occur when the tightly regulated inflammatory network is out of balance and it is now clear that this can eventually cause substantial harm to own cells and tissues. LÄS MER

  5. 4. Streptococcal virulence and the coagulation system

    Författare :Kristofer Wollein Waldetoft; Infektionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Streptococci; virulence; coagulation; intrinsic pathway; evolution;

    Sammanfattning : This thesis explores streptococcal virulence from both mechanistic and evolutionary perspectives, where the mechanistic studies focus on interactions with the human coagulation system. We describe interactions between streptococcal surface proteins and components of the intrinsic pathway of coagulation and the kallikrein-kinin system in human plasma, as well as to how these surface proteins are produced in different growth phases. LÄS MER

  7. 5. Arterial Injury due to Infections in Early Life-A Possible Link in Coronary Heart Disease (Functional and Structural Studies in Animals and Children)

    Författare :Petru Liuba; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatri; Pediatrics; Kardiovaskulära systemet; Cardiovascular system; cardiovascular risk factors; thickening; infection; endothelial dysfunction;

    Sammanfattning : Although the clinical manifestations of atherosclerotic CHD occur in adult life, the preclinical phase begins long before, seemingly already in childhood. There is supportive evidence from both epidemiological studies and animal experiments that infections could contribute to the pathogenesis of arterial disease, including atherosclerosis. LÄS MER