Sökning: "keratinocyte"

Visar resultat 6 - 10 av 48 avhandlingar innehållade ordet keratinocyte.

  1. 6. Retinoic Acid Metabolism Blocking Agents and the Skin : In vivo and in vitro Studies of the Effects on Normal and Diseased Human Epidermis

    Författare :Elizabeth Pavez Loriè; Anders Vahlquist; Hans Törmä; Marie Virtanen; Helen Håkansson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP; CYP26; retinoids; vitamin A; RAMBA; metabolism; keratinocyte; epidermis; retinoid regulated genes; Dermatology and venerology; Dermatologi och venerologi;

    Sammanfattning : Retinoic Acid Metabolism Blocking Agents (RAMBAs) increase the endogenous levels of all-trans retinoic acid (RA) by inhibiting CYP26 enzymes. Thus they are believed to mimic the effects of retinoid treatment. Their mechanism of action and effects on vitamin A metabolism in keratinocytes are however uncertain. LÄS MER

  3. 7. CCN2 – Keratinocyte Interactions In Vitro and In Vivo

    Författare :Elizabeth Kiwanuka; Bengt Gerdin; Kristofer Rubin; Filip Farnebo; Uppsala universitet; []
    Nyckelord :CCN2; connective tissue growth factor; keratinocytes; re-epithelialization; cell migration; cell signaling; Plastikkirurgi; Plastic Surgery;

    Sammanfattning : Cutaneous wound healing is a complex process involving the migration of inflammatory cells to the wound site, deposition of extracellular matrix, and the reestablishment of an intact epithelial barrier. Re-epithelialization depends on the proliferation and directional migration of keratinocytes from the wound edges. LÄS MER

  4. 8. The role of miR-203 in keratinocyte biology and psoriasis

    Författare :Tianling Wei; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Psoriasis is one of the most common chronic inflammatory skin diseases. It is a life long suffering disease affecting approximately 2 to 3% of the population in Scandinavia. Significant progress has been made to understand the cellular immunology and biology of psoriasis. LÄS MER

  5. 9. The effects of plasminogen deficiency on the healing of tympanic membrane perforations

    Författare :Annika Hansson; Sten Hellström; Diana Berggren; Tor Ny; Magnus von Unge; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tympanic membrane; macrophages; neutrophils; fibrin ogen ; inflammation; keratinocyte migration; wound healing; uPA; tPA; in vitro; Otorhinolaryngology; Otorhinolaryngologi;

    Sammanfattning : The healing of tympanic membrane (TM) perforations is a complex wound healing process including inflammation, migration of keratinocytes and tissue remodelling. Most TM perforations in human heal spontaneously, however some perforations become chronic, and the reason to why is still largely unknown. LÄS MER

  7. 10. Epidermal keratinocytes studied by X-ray microanalysis, with special reference to contact dermatitis : In vivo and in vitro studies of functional changes in human cells

    Författare :Anders Grängsjö; Uppsala universitet; []
    Nyckelord :Medical sciences; X-ray microanalysis; elements; epidermis; keratinocytes; proliferation; cell membrane damage; Ki67; irritants; intracellular elemental content; keratinocyte culture; HaCaT; NHEK; RT-PCR; immunohistochemistry; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; anatomi; Human Anatomy;

    Sammanfattning : By determining the intracellular elemental content, information can be obtained on the physiological status of cells. The cellular content of sodium, magnesium, phosphorus, sulfur, chloride, potassium and calcium can be indicative for proliferation, cell membrane damage or cell death. LÄS MER