Sökning: "keratinocyte"

Visar resultat 21 - 25 av 48 avhandlingar innehållade ordet keratinocyte.

  1. 21. Studies on molecular regulation of inflammation in cutaneous lupus erythematosus

    Författare :Vilija Oke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Lupus erythematosus (LE) is an autoimmune disease with a wide range of clinical manifestations. This spectrum spans from limited cutaneous disease to life-threatening rheumatic disorder involving vital organs. Sun exposure is an evident exogenous trigger of both cutaneous (CLE) and systemic LE (SLE). LÄS MER

  3. 22. Understanding the role of non-coding RNAs in skin homeostasis and cancer

    Författare :Kunal Das Mahapatra; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The epidermis is a stratified epithelium with continuous self-renewing capacity. As the outermost layer of our body, it provides a protective barrier against external trauma, produces pigmentation, and keeps the skin hydrated. Keratinocytes are the primary constituent cells type within the epidermis. LÄS MER

  4. 23. Cobalt in the hard metal production industry : exposure via inhalation and skin and the inflammatory response in human keratinocytes

    Författare :Maria Klasson; Eva Särndahl; Håkan Westberg; Magnus Lindberg; Alexander Persson; Kristina Jakobsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cobalt; cobalt chloride; skin; HaCaT; in vitro; cell viability; pro-inflammatory cytokines; NLRP3 inflammasome;

    Sammanfattning : Cobalt is a strong sensitizer and can cause contact allergy upon both direct contact or from airborne exposure on the skin. In the skin, keratinocytes are the first cells to come in contact with the metal and will react and respond to the danger by triggering an alarm system resulting in an inflammatory response in the skin. LÄS MER

  5. 24. Psoriasis : from transcriptome to miRNA function and biomarkers

    Författare :Lorenzo Pasquali; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Psoriasis is a chronic inflammatory, immune-mediated skin condition that affects in average 2 to 3% of the world population, phenotypically characterized by red and scaly plaques on the skin of affected patients. It is a multifactorial disorder, in which both genetic predisposition and environment play key roles. LÄS MER

  7. 25. Plasminogen : a novel inflammatory regulator that promotes wound healing

    Författare :Yue Shen; Tor Ny; Gunilla Høyer-Hansen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasminogen; inflammation; wound healing; diabetic wounds; tympanic membrane perforations; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : The plasminogen activator (PA) system has been shown to be intimately involved in wound healing. However, the role of this system in the initiation and resolution of inflammation during healing process remained to be determined. LÄS MER