Avancerad sökning

Hittade 2 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Tissue kallikrein: pathophysiological role in acute pancreatitis

   Författare :Mats Bläckberg; Helsingborg Kliniska Vetenskaper; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute pancreatitis; aprotinin; alpha-macroglobulin; alpha1-proteinase inhibitor; turn over; kinin B2 receptor; kallidin; bradykinin; Tissue kallikrein; kallistatin; Surgery; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : Tissue kallikrein releases pharmacollogically highly active kinins from kininogen. Many other enzymes may also release kinins. The aim of the study was to clarify the pathophysiological role of tissue kallikrein in acute pancreatitis. Two sensitive and specific radioimmunoassays for porcine and human tissue kallikrein were developed. LÄS MER

3. 2. The Role of Membrane Trafficking in G Protein-Coupled Receptor Regulation

   Författare :Johan Enquist; Drug Target Discovery; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; downregulation; recycling; resensitization; desensitization; GPCR; membrane trafficking;

   Sammanfattning : Movements of a receptor in the plasma membrane and within the cell influence receptor function and physiology. I have investigated the role of such movements, generally known as membrane trafficking, in G protein-coupled receptor regulation. LÄS MER