Sökning: "jon tsai"

Hittade 1 avhandling innehållade orden jon tsai.

1. 1. Parathyroid hormone-related protein (PTHrP), calcium and human osteoblast-like cells

   Författare :Jon A Tsai; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :hOB cells; PTHrP; cAMP; IGFs; IGFBPs; IL-1ß; TGF-ß; [Ca 2 ]i; [Ca2 ]O;

   Sammanfattning : Parathyroid hormone-related protein (PTHrP) may cause humoral hypercalcernia of malignancy (HHM) when overproduced by malignant tumors, but is also produced in lower amounts under normophysiological conditions in practically all cell types, including osteoblasts. One of the aims of the present study was to investigate interactions between PTHrP and osteoblasts, to elucidate bone-regulating functions of PTHrP. LÄS MER