Sökning: "joint disease"

Visar resultat 21 - 25 av 295 avhandlingar innehållade orden joint disease.

  1. 21. Osteoarthritis in temporomandibular joint internal derangement

    Författare :Diana Paegle; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Temporomandibular joint; internal derangement; osteoarthritis;

    Sammanfattning : Internal derangement of the temporomandibular joint is the most common diagnosis leading to joint surgery. Two variants of internal derangement exist, painful clicking and chronic closed lock. Painful clicking is characterized by no or minor arthritic changes. LÄS MER

  2. 22. Neuropeptides in temporomandibular joint arthritis

    Författare :Anna Appelgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Adjuvant; Arthritis; Calcitonin gene-related peptide; Glucocorticosteroids; Hippocampus; Hyperalgesia; Hypothalamus; Hypothalamo-pituitary-adrenal axis; Intra-articular temperature; Neurokinin A; Neuropeptides; Neuropeptide Y; Nociception; Pain; Pituitary; Pressure pain threshold; Rheumatoid arthritis; Substance P; Synovial fluid; Temporomandibularjoint; Visual analog scale;

    Sammanfattning : Involvement of the peripheral and central nervous systems in the pathophysiology of arthritis has been suggested and neuropeptides are thought to participate in the mediation and modulation of the inflammatory process. The main objective of the clinical studies was to investigate the relationship between the presence of neuropeptides in the synovial fluid of the temporomandibular joint (TMJ) and the stomatognathic symptoms and signs, including the intra-articular temperature (IAT), in patients with TMJ arthritis. LÄS MER

  3. 23. Studies of the synovial membrane in chronic rheumatic joint disease

    Författare :Erik af Klint; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: The synovial membrane (SM) outlines the inner cavity of synovial joints except for cartilage surfaces. The SM is the target organ of immune-mediated responses in chronic arthritis, including rheumatoid arthritis (RA). RA is a common joint disease (prevalence of 0.5-1. LÄS MER

  4. 24. Temporomandibular joint involvement by systemic inflammatory disease with reference to pain modulation and joint tissue destruction

    Författare :Ülle Voog; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Acute phase proteins; Computed tomography; Cytokines; Granisetron; Inflammation; Pain; Serotonin; Temporomandibular joint; Visual Analogue Scale.;

    Sammanfattning : Systemic inflammatory diseases may cause progressive destruction in the temporo-mandibular joint (TMJ). Involvement of this joint is associated with many clinical signs and symptoms of which pain is a major problem. LÄS MER

  5. 25. Cartilage destruction - Release of type IX collagen in joint disease

    Författare :Mikael Danfelter; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cartilage destruction; matrix metalloproteinase 13; ECM; assay; neoepitope; NC4 domain; Type IX collagen; fragment;

    Sammanfattning : Cartilage is of vital importance for the function of joints. It is characterized by a prominent extracellular matrix (ECM) that is produced and maintained by relatively few cells of one type, the chondrocyte. LÄS MER