Sökning: "jigsaw puzzle"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden jigsaw puzzle.

1. 1. Topics in discrete random structures

   Författare :Anders Martinsson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; First--passage percolation; Cartesian power graph; third moment argument; jigsaw puzzle; shotgun assembly; monotone paths; non-Markovian coupling; high dimension; coupling inequality; monotone paths;

   Sammanfattning : This thesis presents four papers on problems in discrete probability. A common theme of the articles is to take some class of discrete structures, impose some randomness, and then consider what happens asymptotically as the size of the structure tends to infinity. LÄS MER

3. 2. A multivariate approach to characterization of drug-like molecules, proteins and the interactions between them

   Författare :Anton Lindström; Anna Linusson; Fredrik Almqvist; Anders Karlén; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; binding affinity; prediction; CAMD; principal component analysis PCA ; partial least squares projections to latent structures PLS ; MM-GB-SA; MM-PB-SA; docking; geometry optimization; protein secondary structure characterization; implicit solvent; generalized-Born; Poisson-Boltzmann; molecular mechanics MM ; drug discovery; bindningsaffinitet; prediktion; dockning; geometrioptimering; sekundärstruktur; matematisk vattenmodel; generalized-Born; Poisson-Boltzmann; molekylmekanik MM ; läkemedelsdesign; principal komponent analys PCA ; partial least squares projections to latent structures PLS ; MM-GB-SA; MM-PB-SA; Other chemistry; Övrig kemi;

   Sammanfattning : En sjukdom kan många gånger härledas till en kaskadereaktion mellan proteiner, co-faktorer och substrat. Denna kaskadreaktion blir många gånger målet för att behandla sjukdomen med läkemedel. För att designa nya läkemedelsmoleyler används vanligen datorbaserade verktyg. LÄS MER

4. 3. The Intensive Care Unit syndrome/delirium, patients' perspective and clinical signs

   Författare :Anetth Granberg Axèll; Anestesiologi och intensivvård; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care; delirium; ICU-syndrome; acute confusion; psychosis; critical care; experiences; sleep-deprivation; sensory overload; sensory underload; Anaesthesiology; environment.; Anestesiologi; intensivvård;

   Sammanfattning : When a person becomes critically ill, injured and/or undergoes major surgery and requires intensive care, a complex dilemma can arise. The condition of the illness, the specific caring situation and the environment lead to significant changes and effects in the senses and perceptional abilities. LÄS MER

5. 4. Prediction, Design and Determination of Protein Structures

   Författare :Sebastian Rämisch; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein design; Rosetta; Fold-and-Dock; leucine rich repeat proteins; coiled-coils; molecular replacement; ab initio phasing; temperature stability; fluorescent proteins;

   Sammanfattning : The three-dimensional structure of protein is encoded in its amino acid sequence. Modern structure prediction algorithms make it possible to predict the structure of small proteins using sequence information alone. LÄS MER

7. 5. Inflammation and Intestinal Homeostasis-Associated Genes in Colorectal Cancer

   Författare :Jonas Ungerbäck; Peter Söderkvist; Martin Hallbeck; Kari Hemminki; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : Colorectal cancer (CRC) is a global ‘killer’ and every year more than 1.2 million new individuals are affected and approximately 600 000 succumb to the disorder. Several mechanisms such as inactivation of tumor suppressor genes, activation of oncogenes and dysregulation of cell fate determinating pathways e.g. LÄS MER