Sökning: "jens carlsson"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden jens carlsson.

  1. 1. Challenges in Computational Biochemistry: Solvation and Ligand Binding

    Författare :Jens Carlsson; Johan Åqvist; Chris Reynolds; Uppsala universitet; []
    Nyckelord :Molecular biology; computer simulations; molecular dynamics; solvation free energy; Generalized-Born; Poisson-Boltzmann; ligand binding; binding free energy; linear interaction energy; binding entropy; hydration entropy; Molekylärbiologi;

    Sammanfattning : Accurate calculations of free energies for molecular association and solvation are important for the understanding of biochemical processes, and are useful in many pharmaceutical applications. In this thesis, molecular dynamics (MD) simulations are used to calculate thermodynamic properties for solvation and ligand binding. LÄS MER

  2. 2. Engineering of IoT Automation Systems

    Författare :Oscar Carlsson; Jerker Delsing; Jens Eliasson; Birgit Vogel-Heuser; Luleå tekniska universitet; []
    Nyckelord :ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; Industrial Electronics; Industriell elektronik;

    Sammanfattning : Major societal challenges such as environmental sustainability, availability of energy and raw materials, and globalisation are creating new requirements for many actors in society. These new requirements relate to efficiency, flexibility, sustainability, and competitiveness. LÄS MER

  3. 3. Effects of cold and hand-arm vibration on the peripheral neurosensory and vascular system : an occupational perspective

    Författare :Daniel Carlsson; Jens Wahlström; Tohr Nilsson; Erik Nordh; Hans Pettersson; Tiina Ikäheimo; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hand-arm vibration; Raynaud’s phenomenon; paresthesia; sensation of cold; hand-arm vibration syndrome; quantitative sensory testing; cold sensitivity; cold; cold exposure; frostbite; Sweden; cold injury; military; Occupational and Environmental Medicine; arbets- och miljömedicin;

    Sammanfattning : Background In Swedish working life, exposure to cold and exposure to hand-arm vibration (HAV) are two common health hazards. Health effects of HAV in the neurosensory, vascular and musculoskeletal systems are collectively denoted hand-arm vibration syndrome (HAVS), and have been thoroughly studied. LÄS MER

  4. 4. Meeting increased logistical demands : Developing as a small- and medium-sized system supplier

    Författare :Inga-Lill Carlsson; Mats Abrahamsson; Håkan Aronsson; Jens Hultman; Lars Bengtsson; Linköpings universitet; []

    Sammanfattning : Many subcontractors choose to implement a strategy of “system supply” in order to meetincreasing global competition. They are then confronted with increased demands to take agreater overall responsibility in this role. LÄS MER

  5. 5. Investigations of Strategies to Counteract Proinflammatory Cytokines in Experimental Type 1 Diabetes

    Författare :Andreas Börjesson; Stellan Sandler; Annika Carlsson; Jens Nielsen; Uppsala universitet; []
    Nyckelord :AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Type 1 diabetes; proinflammatory cytokines; SOCS-3; pancreatic islets; inducible nitric oxide synthase; insulin secretion; NOD mice; islet transplantation; proinsulin conversion; streptozotocin; prolactin; Medicine; Medicin;

    Sammanfattning : Type 1 diabetes (T1D) is a chronic autoimmune disease targeted against the pancreatic β-cells. Proinflammatory cytokines are considered to play a major role in the destruction of the insulin-producing β-cells. This thesis studied strategies to counteract proinflammatory cytokines in experimental T1D. LÄS MER