Sökning: "janet cunningham"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden janet cunningham.

1. 1. Tumour Biological Factors Characterizing Metastasizing Serotonin-producing Ileocaecal Carcinoids

   Författare :Janet Lynn Cunningham; Eva Tiensuu Janson; Kjell Öberg; Irvin M. Modlin; Uppsala universitet; []
   Nyckelord :Internal medicine; endocrine tumour; midgut carcinoid; serotonin-producing neuroendocrine carcinoma; prognosis; morphology; tachykinin; connective tissue growth factor; islet autoantigen-2; morphology; carcinoid syndrome; Invärtesmedicin;

   Sammanfattning : In this study, metastasizing serotonin-producing ileocaecal carcinoid tumours (MSPCs) were examined for biological characteristics that could be used to define clinically relevant subgroups within this patient population. Possible targets for new treatment options were also explored. LÄS MER

3. 2. Pregnancy—A Critical Time for Mental Health : Interrogating Psychiatry with Microbiota-Gut-Brain Axis and Autonomic Nervous System Biomarkers

   Författare :Mary C. Kimmel; Alkistis Skalkidou; Janet Cunningham; Emma Fransson; Samantha Meltzer-Brody; Susan Garthus-Niegel; Uppsala universitet; []
   Nyckelord :pregnancy; heart rate variability HRV ; microbiome; depression; anxiety; self-efficacy; cytokines; biomarkers;

   Sammanfattning : Perinatal mood and anxiety disorders (PMADs) are common and impact the parent and child beyond the perinatal period of pregnancy and postpartum. The aim of this thesis was to study biomarkers that might reflect perinatal mental health. LÄS MER

4. 3. Exploring Links between Melatonin, Inflammation and Depression

   Författare :Isak Sundberg; Janet Cunningham; Lisa Ekselius; Daniel Lindqvist; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; melatonin; inflammation; depression; biomarkers; cytokines; anxiety; hepatitis C; Psychiatry; Psykiatri;

   Sammanfattning : Major depressive disorder (MDD) is one of the leading global causes of disease burden. Worse yet, about one third of the patients with MDD do not experience a remission with current treatments. LÄS MER

5. 4. Immunometabolic patterns in psychiatric disease

   Författare :Mikaela Syk; Janet Cunningham; Lisa Ekselius; Annica J. Rasmusson; Robert Fredriksson; Brenda Penninx; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Psychiatry; Human; Autoimmunity; Cytokines; Inflammation; Adiponectin; Leptin; CNS damage; NfL; Tau; GFAp; Biomarkers; Depression; Neuroticism; Bulimia nervosa; Psychiatry; Psykiatri;

   Sammanfattning : Many forms of immune system dysregulation are linked to psychiatric disorders. This thesis examines specific types of immune dysregulation in broad cohorts with psychiatric disease. The first section focuses on adipokines and other immunometabolic biomarkers and their interaction with state vs. trait symptoms. LÄS MER

7. 5. Melatonin and its receptors in the normal human gastrointestinal tract, pancreas and in small intestinal neuroendocrine tumours

   Författare :Fanny Söderquist; Janet Cunningham; Lisa Ekselius; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : Melatonin, “the hormone of darkness” is well known to regulate sleep and circadian rhythm. However, melatonin is also present in numerous peripheral tissues and the number of actions assigned to this neurohormone is growing steadily. LÄS MER