Sökning: "itl vitro expression"

Hittade 1 avhandling innehållade orden itl vitro expression.

  1. 1. Molecular analysis of mutated P450c21 in congenital adrenal hyperplasia

    Författare :Svetlana Lajic; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Congenital adrenal hyperplasia; 21-hydroxylase deficiency; P450c21; itl vitro expression; COS- I; functional analysis; prenatal treatment;

    Sammanfattning : Defects in cytochrome P450c21 (21-hydroxylase, 210H) are the most common causes of congenital adrenal hyperplasia (CAH). This recessively inherited disorder demonstrates a wide spectrum of severity as a consequence of impaired production of cortisol and aldosterone and excessive secretion of adrenal androgens. LÄS MER