Sökning: "isozymes"

Visar resultat 1 - 5 av 30 avhandlingar innehållade ordet isozymes.

  1. 1. Structural / functional studies on human alkaline phosphatases

    Författare :Alexey Kozlenkov; Jose-Luis Millan; Hans Jörnvall; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicine; mutagenesis; enzyme kinetics; computer modeling; crystallography; natural substrates; uncompetitive inhibition; isozymes; gene families; Biomedicin; Microbiology; Mikrobiologi; medicinsk genetik; Medical Genetics;

    Sammanfattning : The recent elucidation of the three-dimensional structure of human placental alkaline phosphatase (PLAP) has enabled me to perform structural studies aimed at characterizing the properties of human PLAP and tissue-nonspecific AP (TNAP) as paradigms for mammalian APs in general, using site-directed mutagenesis, protein expression, kinetic analysis and computer modeling. In Paper I, we found that a single critical E429G substitution explains the difference in stability and kinetics between the common allelic variants of PLAP and the D allozyme. LÄS MER

  3. 2. Genetic variation and sexual reproduction in a moss with dwarf males, Homalothecium lutescens

    Författare :Frida Rosengren; Biodiversitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bryophytes; mosses; dwarf males; sexual reproduction; genetic variation; genetic structure; inbreeding; isozymes; allozymes; SNP; sporophytes; spore; fertilization; fertility;

    Sammanfattning : Dwarf males occur in many unrelated groups of organisms. Among land plants they are unique to mosses. Moss dwarf males originate from male spores that land and germinate on the female where their final size is restricted to a few mm. Fertilization in mosses occur over short distances with swimming spermatozoids. LÄS MER

  4. 3. Evaluation of deoxythymidine kinase isozymes as diagnostic markers

    Författare :Clas F. R. Källander; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  5. 4. Amino acid naphthylamidase isozymes in human cells grown in vitro : Hormonal regulation and isozyme differentiation in cancer cells and normal cells

    Författare :Erik Lundgren; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The elucidation of regulatory mechanisms in higher organisms represents a front line problem in biochemical genetics. In Man the only material available for experimental studies of regulatory mechanisms is cells cultured in vitro. LÄS MER

  7. 5. Cytochromes P-450 in biosynthesis of bile acids and metabolism of vitamin D3 : studies on cytochrome P-450 isozymes in rat liver microsomes

    Författare :Stefan Andersson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER