Sökning: "isotope selectivity"
Visar resultat 1 - 5 av 8 avhandlingar innehållade orden isotope selectivity.
1. Palladium(II)-Catalyzed Oxidative Carbocyclization/Functionalization of Allenynes
Sammanfattning : The selective formation of carbon-carbon bonds constitutes a key transformation in organic synthesis with useful applications in pharmaceutical or material industry. A particularly versatile tool for carbon-carbon as well as carbon-heteroatom bond formation is palladium catalysis, which allows for mild and selective routes even towards complex structures. LÄS MER
2. Atomic laser resonance ionization mass spectrometry
Sammanfattning : .... LÄS MER
3. Iridium-Catalyzed C−H Activation Methods for Late-Stage Functionalization of Pharmaceuticals
Sammanfattning : C-H activations have over the recent decades risen from a mere curiosity to a viable synthetic strategy. However, challenges in terms of accessible transformations, selectivity and functional group tolerance limit the widespread applicability of this approach. LÄS MER
4. Computer Simulation of Protein Tyrosine Phosphatase Reaction Mechanisms and Dihydrofolate Reductase Inhibition
Sammanfattning : Protein tyrosine phosphatases catalyse the hydrolysis of phosphotyrosine residues in proteins, which is an important reaction in the cell signalling system. The three dimensional structure of such a protein tyrosine phosphatase has been used in a computational study of the reaction mechanism at the atomic level. LÄS MER
5. Palladium(II)-Catalyzed Oxidative Carbocyclization/Functionalization of Allenynes
Sammanfattning : Palladium catalysis has emerged as an outstanding tool in synthetic organic chemistry for the mild and selective formation of carbon-carbon and carbon-heteroatom bonds. This thesis has been directed towards the extension of palladium(II)-catalyzed carbocyclization chemistry under oxidative conditions. LÄS MER
