Sökning: "isothiocyanate"
Visar resultat 1 - 5 av 19 avhandlingar innehållade ordet isothiocyanate.
1. New insights in contact allergy and drug delivery. A study of formulation effects and hapten targets in skin using two-photon fluorescence microscopy
Sammanfattning : The skin is a remarkable barrier, protecting us from invasion of e.g. harmful microorganisms and UV-radiation. However, the skin is not adopted to resist repeated exposure to the multitude of xenobiotics introduced into modern society. LÄS MER
2. Analytical methodologies for common skin allergens : Organic thioureas, isothiocyanates and fragrance hydroperoxides in everyday life products
Sammanfattning : This thesis describes analytical methodologies for the determination of important skin-sensitizing chemicals in two types of commercial items: chloroprene rubber and fragrance products which are both well-known to be associated with contact allergy.Chloroprene rubber (neoprene) is widely used in different applications and products, such as bags, gloves, wetsuits, braces, mouse pads et c. LÄS MER
3. Improved techniques for CE and MALDI-MS including microfluidic hyphenations foranalysis of biomolecules
Sammanfattning : In this thesis, improved techniques for biomolecule analysis using capillary electrophoresis (CE) and matrix-assisted laser desorption/ionization-mass spectrometry (MALDI-MS) and hyphenations between those have been presented.A pre-concentration method which is possible to apply in both techniques, has also been investigated. LÄS MER
4. Salvadora persica (MISWAK) : an effective way of killing oral pathogens
Sammanfattning : Mechanical removal of dental plaque is regarded as an effective means of controlling the progression of dental caries and periodontal disease. The habitual use of chewing sticks (Miswak) as an oral hygiene method is still wildly spread throughout parts of Asia, Africa, and the Middle East. LÄS MER
5. Isothiocynates as skin sensitizers. Bioactivation and distribution in skin and draining lymph nodes
Sammanfattning : Development of contact dermatitis can be caused by electrophilic compounds (haptens) or prohaptens that come into contact with the skin. A prohapten is a compound seemingly harmless at first sight that can be transformed into reactive metabolites by metabolizing enzymes in the skin to become a hapten. LÄS MER