Sökning: "islets of Langerhans"

Visar resultat 6 - 10 av 107 avhandlingar innehållade orden islets of Langerhans.

  1. 6. Physiological Studies of Native and Stem Cell-Derived Islets

    Författare :Daniel Norman; Per-Ola Carlsson; Daniel Espes; Helge Ræder; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Irisin; CART; Islet blood flow; Islets of Langerhans; Stem cell-derived islets; Fysiologi; Physiology; Medical Cell Biology; Medicinsk cellbiologi;

    Sammanfattning : In type 1 and type 2 diabetes, the β-cells of the islets of Langerhans are either destroyed by the immune system or stressed due to peripheral insulin resistance. To improve the life of patients with these diseases, new treatments are needed. LÄS MER

  2. 7. Generation of oscillatory Ca2+ signalling in pancreatic ß-cells and islets of Langerhans : roles of voltage-dependent and store-operated entry and intracellular mobilization of Ca2+

    Författare :Yi-Jia Liu; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 8. Imaging Islets of Langerhans by Positron Emission Tomography : Quantification of Beta-Cell Mass in the Native Pancreas and the Islet Graft

    Författare :Olof Eriksson; Anders Sundin; Olle Korsgren; Bengt Långström; Bo Nilsson; Håkan Ahlström; Habib Zaidi; Uppsala universitet; []
    Nyckelord :Positron Emission Tomography; [18F]FDG; dihydrotetrabenazine; Islet transplantation; IBMIR; beta-cell mass; MEDICINE; MEDICIN;

    Sammanfattning : Type 1 and 2 Diabetes Mellitus are a growing health problem throughout the world. There is an increasing  need for methodologies, which are both reliable and non-invasive to measure the amount of insulin-producing tissue (Beta-cell mass, or BCM), as well as rapidly quantify changes in the BCM due to the onset of disease, beta-cell replacement therapy, or other treatments. LÄS MER

  4. 9. Evaluation of Alginate Microcapsules for Use in Transplantation of Islets of Langerhans

    Författare :Aileen King; Simon Howell; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Alginate; biocompatibility; cytokines; epimerases; islet transplantation; microencapsulation; Cellbiologi; Cell biology; Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Sammanfattning : Transplantation of islets of Langerhans is a potential treatment of type 1 diabetes that aims to restore normal glucose homeostasis. Microencapsulation of islets could enable transplantation in the absence of immunosuppression, which would be beneficial as the side effects associated with immunosuppression outweigh the potential benefits of islet transplantation. LÄS MER

  5. 10. Microcirculation in Transplanted Islets of Langerhans

    Författare :Richard Olsson; Uppsala universitet; []
    Nyckelord :;

    Sammanfattning : .... LÄS MER