Sökning: "islet transplantation"
Visar resultat 21 - 25 av 69 avhandlingar innehållade orden islet transplantation.
21. Evaluation of Alginate Microcapsules for Use in Transplantation of Islets of Langerhans
Sammanfattning : Transplantation of islets of Langerhans is a potential treatment of type 1 diabetes that aims to restore normal glucose homeostasis. Microencapsulation of islets could enable transplantation in the absence of immunosuppression, which would be beneficial as the side effects associated with immunosuppression outweigh the potential benefits of islet transplantation. LÄS MER
22. Imaging Islets of Langerhans by Positron Emission Tomography : Quantification of Beta-Cell Mass in the Native Pancreas and the Islet Graft
Sammanfattning : Type 1 and 2 Diabetes Mellitus are a growing health problem throughout the world. There is an increasing need for methodologies, which are both reliable and non-invasive to measure the amount of insulin-producing tissue (Beta-cell mass, or BCM), as well as rapidly quantify changes in the BCM due to the onset of disease, beta-cell replacement therapy, or other treatments. LÄS MER
23. Engraftment of Pancreatic Islets in Alternative Transplantation Sites and the Feasibility of in vivo Monitoring of Native and Transplanted Beta-Cell Mass
Sammanfattning : Islet transplantation is a possible curative treatment for type 1 diabetes (T1D). Currently the liver dominates as implantation site, despite the many challenges encountered at this site.Acute hypoxia in islets transplanted to muscle and omentum, two possible alternative sites, was prevailing. LÄS MER
24. In vivo imaging of islet cells and islet revascularization
Sammanfattning : Glucose homeostasis depends on the release of insulin from the pancreatic beta-cell. Impaired insulin release is a hallmark of diabetes mellitus. LÄS MER
25. Type 1 diabetes : the autoimmune process and islet transplantation
Sammanfattning : Type 1 diabetes (T1D) is an autoimmune disease characterized by the selective loss of the insulin-producing β-cells residing in the islets of Langerhans in the pancreas. Cytokines are involved in diabetes development in the nonobese diabetic (NOD) mouse model. LÄS MER