Sökning: "isatin"

Hittade 4 avhandlingar innehållade ordet isatin.

1. 1. Bio-based nonionic antimicrobial polymers with isatin or indole functionality

   Författare :Xiaoya Li; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; antimicrobial polymers; nonionic; isatin; indole; miscibility; hemolytic activity; cytotoxicity;

   Sammanfattning : Infections by pathogenic microorganisms remain one of the most serious concerns in several areas, particularly in hygienic applications. Antimicrobials have been used to combat these infections. Using small molecular antimicrobials as additives or coatings is an industrially adopted strategy. LÄS MER

3. 2. Synthetic studies of heterocyclic natural products

   Författare :Jeffrey J Mason; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Heterocycles; alkaloids; natural products; luotonin A; cephalandole A; cephalandole B; benzoxazinone; tryptanthrin; ophiuroidine; pyrroloquinazolinone; isatin; Prey demethylation; pyridinium hydrochloride; demethylation; microwave synthesis;

   Sammanfattning : The methods that were developed for the synthesis of the heterocyclic natural products luotonin A, ophiuroidine, cephalandole B, and the indol-3-yl-benzoxazinones of cephalandole A are described in this thesis. The reoccurrence of the 4(3H)-quinazolinone structure is a common theme throughout these studies, and an overview of some quinazoline chemistry is introduced in the first chapter. LÄS MER

4. 3. Synthesis of indole and oxindole derivates incorporating pyrrolidino, pyrrolo or imidazolo moieties

   Författare :Stanley Rehn; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Isatin; three-component reaction; a-amino acid; azomethine ylide; pyrrolidino-3-spiro-3?-oxindole derivatives; 3-methyleneoxindole derivatives; pyrroloquinolone; TosMIC; ß-carboline; tosylimine; pyrrole; keto-enol tautomerism; indolopyran-2-one; imidazole; benzylimine; tetrahydroindole;

   Sammanfattning : The focus of this thesis is on the synthesis of oxindole- and indole-derivatives incorporating pyrrolidins, pyrroles or imidazoles moieties. Pyrrolidino-2-spiro-3'-oxindole derivatives have been prepared in high yielding three-component reactions between isatin, alpha-amino acid derivatives, and suitable dipolarophiles. LÄS MER

5. 4. Synthesis of indolocarbazoles, bisindoles and related sulfur containing systems

   Författare :Tomasz Janosik; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Alkaloids; bisindoles; dithiins; indoles; indolocarbazoles; metallation; pentathiepins; polysulfides; tetrathiocins; thionation; X-ray crystallography.;

   Sammanfattning : This thesis is focussed mainly on the synthesis and reactions of various indolocarbazoles, bisindoles and related sulfur containing systems, all possessing structural features present in many biologically active, natural or synthetic compounds. In the first part, synthetic routes towards the planar, pentacyclic ring systems of indolo[2,3-c]earbazole and indolo[3,2-a]carbazole are described. LÄS MER