Sökning: "ion exchange chromatography"
Visar resultat 1 - 5 av 56 avhandlingar innehållade orden ion exchange chromatography.
1. Tools for digital twins in continuous downstream processing
Sammanfattning : Biopharmaceuticals are of ever-growing importance for human health. The development and production of biopharmaceuticals has the potential for efficiency improvements by switching from batch-wise to continuous production. LÄS MER
2. Aspects of the Design of Preparative Chromatography for Purification of Antibodies
Sammanfattning : The development of biotechnological products is becoming more and more expensive. One type of protein attracting a great deal of attention in the biopharmaceutical industry is antibodies, which was used in this work. LÄS MER
3. Modeling and Calibration of Preparative Chromatography
Sammanfattning : In my thesis, I have modeled adsorption chromatography and simulated, calibrated, and analyzed models of adsorption chromatography. While my main focus has been modeling and calibration of the models by estimating the parameters, the models used have been partly new. LÄS MER
4. Primary Recovery of Biologically Active Compounds Using Macroporous Monolithic Hydrogels
Sammanfattning : The completion of sequencing of human and other mammalian genomes opens a new era for drug development. New approaches have been proposed for tackling diseases such as development of small molecule therapies based on understanding of human genome and proteome, new proteinous based therapies, where the therapeutic protein can inhibit or modify a certain metabolic pathway or DNA-based therapies delivering a gene into the cell (e. LÄS MER
5. Superporous agarose a new material for chromatography
Sammanfattning : Agarose, the most commonly employed chromatography base material in industrial purification processes for biomolecules – proteins, has almost ideal properties. The major disadvantage of the agarose support is its poor mechanical strength which excludes its use in high speed separations where small particles are needed in order to achieve improved chromatographic efficiency. LÄS MER