Sökning: "invasiveness"

Visar resultat 21 - 25 av 85 avhandlingar innehållade ordet invasiveness.

  1. 21. Virulence determinants of the insect pathogen Bacillus thuringiensis; : Molecular characterization of flagellins and the virulence protease immune inhibitor A

    Författare :Ann Lövgren; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mikrobiologi; Microbiology;

    Sammanfattning : Bacillus thuringiensis (Bt) is a motile, Gram positive, rod-shaped and spore-forminginsect pathogenic bacterium found on plants and in soil. The main insecticidal activityresides in a proteinacious crystal inclusion body (the S-endotoxin), but also the sporesare important for lethality. LÄS MER

  3. 22. Platelets – Multifaceted players in tumor progression and vascular function

    Författare :Yanyu Zhang; Anna-Karin Olsson; Gertraud Orend; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cancer; Tumor; Platelet; HRG; PDGFB; TBK1; NETs; Angiogenesis; EMT; Metastasis; Medicinsk vetenskap; Medical Science; Oncology; Onkologi; Biologi med inriktning mot molekylär cellbiologi; Biology with specialization in Molecular Cell Biology;

    Sammanfattning : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. LÄS MER

  4. 23. Studies on basal cell carcinoma with emphasis on the role of the human homologue of the Drosophila patched gene

    Författare :Anne Birgitte Undén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Basal cell carcinoma BCC ; carcinogenesis; in situ hybridization; linkageanalysis; gene; mutation; PCR; p53; PTCH; SHH; skin; SSCP; stromelysin 3 ST3 ; trichoepithelioma TE ; UVR.;

    Sammanfattning : Basal cell cancer (BCC) is the most common cancer in the Western world. Although BCCs hardly ever metastasize, invasive growth may cause considerable local tissue destruction. Ultraviolet radiation (WR) is presumed to be the predominant environmental factor. LÄS MER

  5. 24. 3D super-resolution microscopy of living cells using reversibly switchable fluorophores

    Författare :Andreas Bodén; Ilaria Testa; Francisco Balzarotti; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RESOLFT; 3D imaging; super-resolution; microscopy; reversibly switchable fluorescent proteins; Biological Physics; Biologisk fysik;

    Sammanfattning : Traditional optical microscopy techniques are limited in spatial resolution due to the wave nature of light. This means that neighboring objects separated by a distance smaller than about 200 nm cannot be distinguished. LÄS MER

  7. 25. Tumor-stroma interactions in hepatocellular carcinoma

    Författare :Nataša Pavlović; Femke Heindryckx; Jessica Maiers; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hepatocellular carcinoma; fibrosis; endoplasmic reticulum stress; unfolded protein response; platelets; P2Y12; Molekylär cellbiologi; Molecular Cellbiology; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : Hepatocellular carcinoma (HCC), a highly deadly primary liver cancer with a rising global incidence and limited therapeutic options, is characterized by a vicious cross-talk between the tumor and its surrounding hepatic stroma. The stromal environment, consisting of hepatic stellate cells (HSC), endothelial cells, resident and infiltrating macrophages and other immune cells, platelets and extracellular matrix (ECM) components, actively contributes to creating an ideal niche for tumor proliferation and invasiveness. LÄS MER