Sökning: "invasiveness"

Visar resultat 1 - 5 av 79 avhandlingar innehållade ordet invasiveness.

  1. 1. Biotic resistance in freshwater fish communities

    Författare :Anna Henriksson; Göran Englund; David Wardle A.; Jun Yu; Sebastian Diehl; Donald Jackson; Umeå universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; biotic resistance; freshwater fish; introductions; invasions; invasion success; invasibility; invasiveness; species richness; saturation; species identity; weighted species richness;

    Sammanfattning : Invasions of non-native species cause problems in ecosystems worldwide, and despite the extensive effort that has been put into research about invasions, we still lack a good understanding for why some, but not other, communities resist these invasions. In this doctoral thesis I test hypotheses on biotic resistance using a large dataset of more than 1000 both failed and successful introductions of freshwater fish into Swedish lakes. LÄS MER

  2. 2. Proteomics of invasiveness of human breast epithelial cells

    Författare :Kah Wai Lin; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mechanisms of malignant transformation and cancer invasion and factors controlling them in response to various stimuli remain elusive. We used proteomics and systems biology to explore these mechanisms in human breast epithelial cells. The objective has been to identify a set of biomarkers for diagnostics and prognostics of breast cancer. LÄS MER

  3. 3. Molecular markers reflecting malignant transformation and tumor progression

    Författare :Patricia Stoltzfus; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Molecular markers; interphase fluorescence in situ hytidization; genetic diagnostic test; laminin-5 gamma2 chain; immunohistochemistry; precancerous lesions; invasiveness; breast cancer; cervical squamous cell carcinoma; tongue carcinoma; vulvar carcinoma;

    Sammanfattning : The early detection of neoplastic lesions is most critical in the successful treatment of malignant disease. This thesis investigates molecular targets for an improved detection and diagnosis of cancer by exploring the value of interphase fluorescence in situ hybridization (FISH) to detect specific chromosomal aneuploidies and gene amplifications, and laminin-5 gamma2 chain expression detected by immunohistochemistry as a marker for invasiveness. LÄS MER

  4. 4. Search for markers and molecular mechanisms of aggressive endometrial cancer : profiling of aggressive vs non-aggressive endometrial cancers

    Författare :Sanaz Attarha; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Endometrial cancer is the seventh frequent type of cancer among women. Identification of new prognostic markers is important to optimize treatment and follow-up of all EC patients. Understanding the molecular mechanisms of carcinogenesis may pave through discovery of further EC molecular markers. LÄS MER

  5. 5. Hormone concentrations during pregnancy and maternal risk of epithelial ovarian cancer

    Författare :Helena Schock; Eva Lundin; Annika Idahl; Renée Turzanski Fortner; Anne Zeleniuch-Jacquotte; Shelley S Tworoger; Umeå universitet; []
    Nyckelord :AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; epithelial ovarian cancer; sex steroid hormones; IGF-I; placental GH; AMH; pregnancy; prospective study; patologi; Pathology;

    Sammanfattning : Background: The aim of this thesis was to study the relationship of pre-diagnostic circulating concentrations of sex steroid hormones (androgens, estradiol, 17-hydroxyprogesterone, and progesterone), growth factors (insulin-like growth factor-I (IGF-I), placental growth hormone (GH)), sex hormone binding globulin (SHBG), and anti-Müllerian hormone (AMH) with risk of epithelial ovarian cancer (EOC) overall, and by tumor invasiveness and histology. A longitudinal study was used to assess patterns of hormonal changes during a single pregnancy, and in two consecutive pregnancies. LÄS MER