Sökning: "invasion"

Visar resultat 16 - 20 av 423 avhandlingar innehållade ordet invasion.

  1. 16. Cell cycle perspectives on breast cancer cell behaviour

    Författare :Pontus Berglund; Malmö Experimentell patologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; invasion; breast cancer; migration; proliferation; cyclin D1; cyclin E;

    Sammanfattning : Uncontrolled proliferation and the capacity to infiltrate surrounding tissues are two important characteristics of aggressive tumour cells. Previous observations in both colorectal cancer and basal cell carcinoma indicated that infiltrative tumour cell behaviour might be counteracted by a high proliferative activity, suggesting a coordination of these two activities at the cellular level. LÄS MER

  3. 17. RsbX and stress response in Listeria monocytogenes

    Författare :Ana Henriques de Oliveira; Jörgen Johansson; Cormac Gahan; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Listeria monocytogenes; SigB; stressosome; RsbX; phosphorylation; growth; competitiveness; motility; energetic cost; homeostasis; stress response; virulence; invasion; molekylärbiologi; Molecular Biology; mikrobiologi; Microbiology;

    Sammanfattning : Listeria monocytogenes is a ubiquitous foodborne Gram-positive bacterium. Despite being mainly a soil bacterium, it can reach the food processing environment and contaminate food destined for human consumption, causing outbreaks. LÄS MER

  4. 18. Regulatory Effects of TGF-β Superfamily Members on Normal and Neoplastic Thyroid Epithelial Cells

    Författare :Åsa Franzén; Paschalis Sideras; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; activin; BMP; cadherin; carcinoma; cell cycle arrest; dedifferentiation; EGF; growth inhibition; invasion; Smad; TGF-β; thyroid; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Thyroid growth and function is partly regulated by growth factors binding to receptors on the cell surface. In the present thesis, the transforming growth factor-β (TGF-β) superfamily members have been studied for their role in regulation of growth and differentiation of both normal and neoplastic thyroid epithelial cells. LÄS MER

  5. 19. The impact of Wnt5a signaling and tumor associated macrophages in breast cancer

    Författare :Catharina Hagerling; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; Wnt5a; E-cadherin; B-catenin; migration; invasion; turnor associated macrophages; CD163; CD68; turnor stroma;

    Sammanfattning : Breast cancer is the most common cancer among women worldwide with approximately 1.150.000 new cases each year and accounting for over 400.000 deaths per year. LÄS MER

  7. 20. Invasive and Metastatic Properties of Advanced Prostate Cancer

    Författare :Karin Jennbacken; Göteborgs universitet; []
    Nyckelord :Prostate cancer; Androgen-independent; Castration-resistant; Metastasis; Invasion; Lymphangiogenesis; Cell adhesion; N-cadherin; VEGF-C; MRI;

    Sammanfattning : Prostate cancer is initially androgen-dependent (AD) and therefore androgen deprivation therapy (ADT) is generally used to treat advanced prostate cancer. However, the long-term treatment effects are insufficient and over time an androgen-independent (AI) tumor relapses, which is generally highly aggressive and metastatic. LÄS MER