Sökning: "invärtesmedicin Klinisk genetik"

Visar resultat 6 - 10 av 70 avhandlingar innehållade orden invärtesmedicin Klinisk genetik.

  1. 6. NO Effect on Inflammatory Reaction in Extracorporeal Circulation : Ex vivo Studies

    Författare :Mika Lahtinen; Jan Borowiec; Per Venge; Vibeke Videm; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Cardiac surgery; extracorporeal circulation; inflammatory reaction; NO; degranulation; neutrophil; eosinophil; basophil; complement; contact system; coagulation; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Nitric oxide (NO) is expressed in inflammatory tissues. However, NO effects are controversial in inflammation; NO is described as acting in a dose dependent manner and possess both pro-inflammatory and anti-inflammatory properties. LÄS MER

  3. 7. Activity and Regulation of Telomerase in Malignant Cells

    Författare :Anna Lindkvist; Ylva Paulsson-Karlsson; Göran Roos; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; apoptosis; ATC; c-Myc; drug sensitivity; ESCC; hTERT; hypoxia; IFN; MM; neuroblastoma; p53; telomerase; TGF-β; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : An important step in tumorgenesis is the acquisition of cellular immortality. Tumor cells accomplish this by activating the enzyme telomerase, and thereby avoiding replicative senescence. The aim of this thesis was to study the activity and regulation of telomerase in a panel of malignant cell types. LÄS MER

  4. 8. Reverse Transcriptase Activity Assays for Retrovirus Quantitation and Characterization

    Författare :Anders Malmsten; Ulf Gyllensten; Clas Källander; Lynn Morris; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; retrovirus; reverse transcriptase; enzyme activity assay; MuLV; HIV; RT purification; viral load; drug susceptibility; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Reverse transcriptase (RT) is a crucial enzyme for retrovirus replication, and its presence in the virion is indispensable for infectivity. This thesis illustrates the use of RT activity assays as tools for quantitation and characterization of different retroviruses, particularly HIV. LÄS MER

  5. 9. Predictors of disease onset and progression in early rheumatoid arthritis : A clinical, laboratory and radiological study

    Författare :Ewa Berglin; Solbritt Rantapää-Dahlqvist; Thomas Skogh; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; early; rheumatoid; arthritis; anti-CCP; antibodies; factors; radiological; outcome; disease; onset; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; medicin; Medicine;

    Sammanfattning : To diagnose rheumatoid arthritis (RA) during the early stages of the disease is often difficult. The disease course shows great inter-individual variation from mild, self-limiting to very severe destruc-tive disease with extra-articular manifestations. LÄS MER

  7. 10. Ventricular Long Axis Function: Amplitudes and Timings : Echocardiographic Studies in Health and Disease

    Författare :Frederick Bukachi; Anders Waldenstrom; Derek Gibson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Echocardiography; Doppler Tissue Imaging; Ageing; coronary disease; left ventricular function; atrial contraction; electromechanical function; coronary angioplasty.; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin; kardiologi; Cardiology;

    Sammanfattning : Background: The ageing process not only increases the risk of coronary artery disease (CAD) but also complicates its diagnosis and treatment. It is therefore important to understand the newer concepts of cardiovascular ageing physiology as well as methods of predicting the outcomes of therapeutic options available for the elderly with severe CAD. LÄS MER