Sökning: "intravital microscopy"

Visar resultat 16 - 20 av 31 avhandlingar innehållade orden intravital microscopy.

  1. 16. Leukocyte rolling and firm adhesion in the microvasculature : functional significance for leukocyte recruitment in inflammation

    Författare :Xun Xie; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :adhesion molecules; blood flow; chemoattractants; endothelium; flowcytometry; fucoidin; heparin; inflammation; integrins; intravital microscopy; leukocyteadhesion; leukocyte extravasation; leukocyte rolling; meningitis; mesentery; microcirculation; ;

    Sammanfattning : Leukocyte recruitment to tissues is a key component in the inflammatory process. In order for circulating leukocytes to extravasate, they need to interact with vascular endothelium in several sequential steps. LÄS MER

  3. 17. Surgical trauma, inflammation and tissue injury

    Författare :Leif Törkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Activated partial thromboplastin time; blood flow; blood pressure; CD18; calcitonin gene-related peptide; dalteparin; glucocorticoids; heparin; intravital microscopy; leukotrienes; myeloperoxidase; neutrophils; stress; surgical flaps; rat;

    Sammanfattning : Surgical tissue trauma is a strong stimulus for local inflammation, including leukocyte recruitment. While such a response may be of importance for the defense against microorganisms, it is also clear that inflammation may contribute to further tissue injury. LÄS MER

  4. 18. Leukocyte-endothelial interactions in arteries in vivo : a new concept in the study of physiology and disease in large blood vessels

    Författare :Einar Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atherosclerosis; leukocyte; cell adhesion molecule; chemokine; shear rate; capture; rolling; adhesion; subendothelial; cytokine; artery; intravital; in vivo;

    Sammanfattning : Pathophysiological events in large blood vessels contribute to immense morbidity and mortality in our society. A major clinical problem is a disease known as atherosclerosis. It involves a slow inflammatory deposition of lipid within the walls of large arteries that with time will weaken the arterial wall. LÄS MER

  5. 19. Neutrophils in atherosclerosis

    Författare :Pierre Rotzius; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Atherosclerosis is a complex inflammatory disease localized in medium-sized and large arteries and it is the most important contributor to cardiovascular disease. Complications of atherosclerosis such as myocardial infarction and stroke are leading causes of mortality in many countries. LÄS MER

  7. 20. On Generation and Function of Neutrophil Extracellular Traps in Abdominal Sepsis

    Författare :Avin Hawez; Kirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Abdominal sepsis; inflamation; neutrophil; neutrophil extracellular traps; mRNA; adhesion.;

    Sammanfattning : AbstractSepsis is a clinical condition that develops when the immune system over-response to an infection. Sepsis can lead to organ failure as well as subsequent death. Sepsis-induced host response involves neutrophil over activation which can lead to self tissue damage. LÄS MER