Sökning: "intratracheal"

Visar resultat 1 - 5 av 11 avhandlingar innehållade ordet intratracheal.

  1. 1. Infections Related to the Use of Medical Devices and Changes in the Oropharyngeal Flora

    Författare :Hulda Thorarinsdottir; Anestesiologi och intensivvård; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thrombosis; critical illness; biofilm; intratracheal intubation; ventilator-associated pneumonia; ; central venous catheters; catheter-related infections; proton pump inhibitors; oropharynx; MICROBIOTA; foreign-body reaction; hemolysis; inflammation;

    Sammanfattning : Background: Humans exist in mutualistic balance with a large range of microbiota. Illness and hospitalization can disturb this balance and contribute to hospital-acquired infections (HAIs), which occur most often in critically ill patients. LÄS MER

  3. 2. DNA lesions and carcinogenicity from the urban air pollutants 2- and 3-nitrobenzanthrone

    Författare :Eszter Nagy; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :3-nitrobenzanthrone; 2-nitrobenzanthrone; diesel exhaust; carcinogenicity; acute toxicity; DNA adducts; oxidative stress; intratracheal; ingestion;

    Sammanfattning : In the early 1990's, Japanese doctors in urban areas discovered an increasing incidence of lung cancer among women, which was not attributed to a change in diet or smoking. This led to a growing investigation of urban air, and subsequently the discovery of 3-nitrobenzanthrone (3-NBA), a pollutant originating from diesel emissions. LÄS MER

  4. 3. Linear and Branched Chitosan Oligomers as Delivery Systems for pDNA and siRNA In Vitro and In Vivo

    Författare :Mohamed Mahmoud Issa; Per Artursson; Arto Urtti; Uppsala universitet; []
    Nyckelord :Medical sciences; Chitosan oligomers; gene delivery; gene expression; pDNA; siRNA; MEDICIN OCH VÅRD;

    Sammanfattning : In this thesis, chitosan, a biocompatible polysaccharide that has been approved as a food additive was selected as a platform for the development of safe, efficient non-viral gene delivery systems to mammalian cells. Previously, chitosan-based gene formulations had been generally associated with high molecular weight chitosans, which were poorly characterised in terms of molecular weight distribution and degree of acetylation. LÄS MER

  5. 4. Interleukin-17 in non-allergic airway inflammation

    Författare :Martti Laan; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; IL-17; airway inflammation; bronchial epithelial cells; neutrophils; T-lymphocytes; IL-8; IL-6; MAP kinases.;

    Sammanfattning : Chronic bronchitis, chronic obstructive pulmonary disease (COPD), bronchial asthma and cystic fibrosis are common clinical disorders all characterized by airway neutrophilia. By releasing proteolytic enzymes and free oxygen radicals, neutrophils can contribute to the main features of these diseases such as airway obstruction, hypersecretion and remodelling. LÄS MER

  7. 5. Engineered nanomaterials in in vivo and in vitro models

    Författare :Laura Abariute; NanoLund: Centre for Nanoscience; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; III-V semiconductor nanowires; Nanoparticle exposure; Mouse exposure; Cell exposure; Nanotoxicology; Nanosafety; Fysicumarkivet A:2018:Abariute;

    Sammanfattning : Nanotechnology and engineered nanomaterials (ENM) empower existing technologies. One of the great examples are III-V semiconductor nanowires (NW), which have a broad application range. The occupational safety and hazard organizations draw attention to ENM, as their physical and chemical characteristics differ from the ones of bulk materials. LÄS MER